E. G. Kulapina, R. K. Mursalov, O. I. Kulapina, V. D. Ankina
{"title":"水介质和生物介质中未改性和改性固体接触式电位计 β-内酰胺传感器的电分析特性","authors":"E. G. Kulapina, R. K. Mursalov, O. I. Kulapina, V. D. Ankina","doi":"10.1134/S002016852314008X","DOIUrl":null,"url":null,"abstract":"<p>A comparative study of the electroanalytical properties of solid-contact sensors (tubular, planar) in solutions of cefuroxime (Cefur), cefotaxime (Ceftx), cefixime (Cefix), and amoxicillin (Amox) is performed. Associates of tetraalkylammonium—tetradecylammonium (TDA) and dimethyldistearylammonium (DMDSA)—with complex compounds of silver(I) and β-lactam antibiotics [Ag(β-lac)<sub>2</sub>]TAA and modifiers such as ZnO, polyaniline, and polyaniline nanotubes are used as electrode-active components (EACs). The sensors under study based on [Ag(Cefur)<sub>2</sub>]TDA and [Ag(Amox)<sub>2</sub>]DMDSA are characterized by a short response time in solutions of cefotaxime, cefuroxime, cefixime, and amoxicillin: 20–25 and 12–17 s for tubular unmodified and modified, respectively; 20–25 and 10–15 s for planar unmodified and modified, respectively. The linear range of electrode functions in solutions of antibiotics is 1 × 10<sup>–4</sup>–1 × 10<sup>–2</sup> mol/L; the limit of detection is 2.5 × 10<sup>–5</sup>–8.9 × 10<sup>–5</sup> mol/L for unmodified, 5.6 × 10<sup>–6</sup>–7.5 × 10<sup>–5</sup> mol/L for modified, and 4.2 × 10<sup>–5</sup>–7.2 × 10<sup>–5</sup> mol/L for planar sensors. The potential drift is 8–12 mV/day for unmodified and 5–7 mV/day for modified planar sensors; the service life is 1.5–2 months. An advantage of planar sensors is their use in microassay detection, which is relevant in the analysis of biological media. Application of solid-contact sensors for determination of the antibiotics under study in model aqueous solutions, medicinal products, and oral fluid in the case of various infectious diseases is demonstrated.</p>","PeriodicalId":585,"journal":{"name":"Inorganic Materials","volume":"59 14","pages":"1418 - 1426"},"PeriodicalIF":0.9000,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Electroanalytical Properties of Unmodified and Modified Solid-Contact Potentiometric β-Lactam Sensors in Aqueous and Biological Media\",\"authors\":\"E. G. Kulapina, R. K. Mursalov, O. I. Kulapina, V. D. Ankina\",\"doi\":\"10.1134/S002016852314008X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A comparative study of the electroanalytical properties of solid-contact sensors (tubular, planar) in solutions of cefuroxime (Cefur), cefotaxime (Ceftx), cefixime (Cefix), and amoxicillin (Amox) is performed. Associates of tetraalkylammonium—tetradecylammonium (TDA) and dimethyldistearylammonium (DMDSA)—with complex compounds of silver(I) and β-lactam antibiotics [Ag(β-lac)<sub>2</sub>]TAA and modifiers such as ZnO, polyaniline, and polyaniline nanotubes are used as electrode-active components (EACs). The sensors under study based on [Ag(Cefur)<sub>2</sub>]TDA and [Ag(Amox)<sub>2</sub>]DMDSA are characterized by a short response time in solutions of cefotaxime, cefuroxime, cefixime, and amoxicillin: 20–25 and 12–17 s for tubular unmodified and modified, respectively; 20–25 and 10–15 s for planar unmodified and modified, respectively. The linear range of electrode functions in solutions of antibiotics is 1 × 10<sup>–4</sup>–1 × 10<sup>–2</sup> mol/L; the limit of detection is 2.5 × 10<sup>–5</sup>–8.9 × 10<sup>–5</sup> mol/L for unmodified, 5.6 × 10<sup>–6</sup>–7.5 × 10<sup>–5</sup> mol/L for modified, and 4.2 × 10<sup>–5</sup>–7.2 × 10<sup>–5</sup> mol/L for planar sensors. The potential drift is 8–12 mV/day for unmodified and 5–7 mV/day for modified planar sensors; the service life is 1.5–2 months. An advantage of planar sensors is their use in microassay detection, which is relevant in the analysis of biological media. Application of solid-contact sensors for determination of the antibiotics under study in model aqueous solutions, medicinal products, and oral fluid in the case of various infectious diseases is demonstrated.</p>\",\"PeriodicalId\":585,\"journal\":{\"name\":\"Inorganic Materials\",\"volume\":\"59 14\",\"pages\":\"1418 - 1426\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inorganic Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S002016852314008X\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganic Materials","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1134/S002016852314008X","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Electroanalytical Properties of Unmodified and Modified Solid-Contact Potentiometric β-Lactam Sensors in Aqueous and Biological Media
A comparative study of the electroanalytical properties of solid-contact sensors (tubular, planar) in solutions of cefuroxime (Cefur), cefotaxime (Ceftx), cefixime (Cefix), and amoxicillin (Amox) is performed. Associates of tetraalkylammonium—tetradecylammonium (TDA) and dimethyldistearylammonium (DMDSA)—with complex compounds of silver(I) and β-lactam antibiotics [Ag(β-lac)2]TAA and modifiers such as ZnO, polyaniline, and polyaniline nanotubes are used as electrode-active components (EACs). The sensors under study based on [Ag(Cefur)2]TDA and [Ag(Amox)2]DMDSA are characterized by a short response time in solutions of cefotaxime, cefuroxime, cefixime, and amoxicillin: 20–25 and 12–17 s for tubular unmodified and modified, respectively; 20–25 and 10–15 s for planar unmodified and modified, respectively. The linear range of electrode functions in solutions of antibiotics is 1 × 10–4–1 × 10–2 mol/L; the limit of detection is 2.5 × 10–5–8.9 × 10–5 mol/L for unmodified, 5.6 × 10–6–7.5 × 10–5 mol/L for modified, and 4.2 × 10–5–7.2 × 10–5 mol/L for planar sensors. The potential drift is 8–12 mV/day for unmodified and 5–7 mV/day for modified planar sensors; the service life is 1.5–2 months. An advantage of planar sensors is their use in microassay detection, which is relevant in the analysis of biological media. Application of solid-contact sensors for determination of the antibiotics under study in model aqueous solutions, medicinal products, and oral fluid in the case of various infectious diseases is demonstrated.
期刊介绍：
Inorganic Materials is a journal that publishes reviews and original articles devoted to chemistry, physics, and applications of various inorganic materials including high-purity substances and materials. The journal discusses phase equilibria, including P–T–X diagrams, and the fundamentals of inorganic materials science, which determines preparatory conditions for compounds of various compositions with specified deviations from stoichiometry. Inorganic Materials is a multidisciplinary journal covering all classes of inorganic materials. The journal welcomes manuscripts from all countries in the English or Russian language.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
