Arantxa Vidal Esteban, Inmaculada Concepción Becerra Fernández, María José Rivero Martin
{"title":"[≥35周新生儿经皮胆红素测定法与血清胆红素之间的相关性]。","authors":"Arantxa Vidal Esteban, Inmaculada Concepción Becerra Fernández, María José Rivero Martin","doi":"10.32641/andespediatr.v95i1.4851","DOIUrl":null,"url":null,"abstract":"<p><p>Clinical control and monitoring of bilirubin in the neonatal stage are essential to avoid toxicity in the central nervous system.</p><p><strong>Objective: </strong>to determine the correlation between transcutaneous bilirubin (TcB) and total serum bilirubin (TSB) levels in newborns ≥ 35 weeks.</p><p><strong>Patients and method: </strong>observational, cross-sectional, analytical, retrospective study that included 90 neonates of gestational age ≥ 35 weeks with mucocutaneous jaundice who underwent TcB and TSB measurement simultaneously between June 1, 2022, and January 31, 2023. Both variables were compared, determining their correlation.</p><p><strong>Results: </strong>the validity indicators were analyzed, obtaining 100% sensitivity and negative predictive value. The mean of TcB determinations was 14.84 mg/dl ± 2.27 and that of TSB was 13.1 mg/dl ± 2.39. The correlation obtained indicates that both variables are related, which is a direct correlation and, according to the prediction equation, there is an appropriate correlation between them. It was determined that TcB overestimated TSB in 95.56% of the determinations, and underestimated TSB in the rest (4.44%). Simultaneous measurements of TcB and TSB were different in all determinations with a mean difference of 1.72 ± 1.48.</p><p><strong>Conclusions: </strong>the non-invasive TcB method can be used as an initial screening tool for the neonatal population ≥ 35 weeks, given its adequate sensitivity and negative predictive value.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"95 1","pages":"34-40"},"PeriodicalIF":0.5000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Correlation between transcutaneous bilirubinometry and serum bilirubin in newborns ≥ 35 weeks].\",\"authors\":\"Arantxa Vidal Esteban, Inmaculada Concepción Becerra Fernández, María José Rivero Martin\",\"doi\":\"10.32641/andespediatr.v95i1.4851\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Clinical control and monitoring of bilirubin in the neonatal stage are essential to avoid toxicity in the central nervous system.</p><p><strong>Objective: </strong>to determine the correlation between transcutaneous bilirubin (TcB) and total serum bilirubin (TSB) levels in newborns ≥ 35 weeks.</p><p><strong>Patients and method: </strong>observational, cross-sectional, analytical, retrospective study that included 90 neonates of gestational age ≥ 35 weeks with mucocutaneous jaundice who underwent TcB and TSB measurement simultaneously between June 1, 2022, and January 31, 2023. Both variables were compared, determining their correlation.</p><p><strong>Results: </strong>the validity indicators were analyzed, obtaining 100% sensitivity and negative predictive value. The mean of TcB determinations was 14.84 mg/dl ± 2.27 and that of TSB was 13.1 mg/dl ± 2.39. The correlation obtained indicates that both variables are related, which is a direct correlation and, according to the prediction equation, there is an appropriate correlation between them. It was determined that TcB overestimated TSB in 95.56% of the determinations, and underestimated TSB in the rest (4.44%). Simultaneous measurements of TcB and TSB were different in all determinations with a mean difference of 1.72 ± 1.48.</p><p><strong>Conclusions: </strong>the non-invasive TcB method can be used as an initial screening tool for the neonatal population ≥ 35 weeks, given its adequate sensitivity and negative predictive value.</p>\",\"PeriodicalId\":72196,\"journal\":{\"name\":\"Andes pediatrica : revista Chilena de pediatria\",\"volume\":\"95 1\",\"pages\":\"34-40\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Andes pediatrica : revista Chilena de pediatria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32641/andespediatr.v95i1.4851\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Andes pediatrica : revista Chilena de pediatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32641/andespediatr.v95i1.4851","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
[Correlation between transcutaneous bilirubinometry and serum bilirubin in newborns ≥ 35 weeks].
Clinical control and monitoring of bilirubin in the neonatal stage are essential to avoid toxicity in the central nervous system.
Objective: to determine the correlation between transcutaneous bilirubin (TcB) and total serum bilirubin (TSB) levels in newborns ≥ 35 weeks.
Patients and method: observational, cross-sectional, analytical, retrospective study that included 90 neonates of gestational age ≥ 35 weeks with mucocutaneous jaundice who underwent TcB and TSB measurement simultaneously between June 1, 2022, and January 31, 2023. Both variables were compared, determining their correlation.
Results: the validity indicators were analyzed, obtaining 100% sensitivity and negative predictive value. The mean of TcB determinations was 14.84 mg/dl ± 2.27 and that of TSB was 13.1 mg/dl ± 2.39. The correlation obtained indicates that both variables are related, which is a direct correlation and, according to the prediction equation, there is an appropriate correlation between them. It was determined that TcB overestimated TSB in 95.56% of the determinations, and underestimated TSB in the rest (4.44%). Simultaneous measurements of TcB and TSB were different in all determinations with a mean difference of 1.72 ± 1.48.
Conclusions: the non-invasive TcB method can be used as an initial screening tool for the neonatal population ≥ 35 weeks, given its adequate sensitivity and negative predictive value.