马蹄内翻足的流行病学特征:哥伦比亚一项监测计划的人口研究。

IF 0.9 4区 医学 Q4 ORTHOPEDICS
Esteban Portilla-Rojas, Pablo Pineda-Sanabria, Lina Ramírez, Maria Isabel Cuevas, Juliana Lores, Karen Sarmiento, Ignacio Zarante
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引用次数: 0

摘要

马蹄内翻足是一种常见的先天性肌肉骨骼畸形,在中低收入国家的发病率为每万名活产儿中有 5-20 例。如果不及时治疗,马蹄内翻足会给儿童带来严重后果:步态障碍、生活质量下降、工作机会受限。我们的目标是了解马蹄内翻足的特征,并确定 2002 年至 2020 年哥伦比亚波哥大和卡利的发病率及相关风险因素。我们采用了回顾性病例对照研究设计,分析了先天性缺陷和孤儿疾病预防与跟踪计划监控系统提供的出生缺陷报告数据。病例包括患有马蹄内翻足的活产或死产婴儿,对照组包括没有先天畸形的婴儿,出生日期和医院均匹配。患病率的计算采用泊松分布(Poisson distribution)的 95% 置信区间,风险因素则通过逻辑回归模型得出的调整几率比进行评估。在 558 255 名新生儿中,共发现 861 例足癣病例,其中 48.20% 为姿势性足癣,15 例为综合征足癣。在波哥大,患病率为每万名活产婴儿中 15.1 例,而在卡利,患病率为每万名活产婴儿中 17.29 例。一级亲属中有马蹄内翻足家族史被认为是马蹄内翻足的一个风险因素。调查马蹄内翻足的风险因素对于预防和降低该人群的发病率具有重要意义。有助于推动政府和医疗保健机构采取旨在提供及时有效治疗的措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological characterization of clubfoot: a population-based study of a surveillance program in Colombia.

Clubfoot is a common musculoskeletal congenital abnormality, with a prevalence of 5-20 cases per 10 000 live births in low to middle-income countries. If left untreated, clubfoot causes severe consequences for the child: gait disturbances, reduced quality of life, and limited work opportunities. Our objective was to characterize clubfoot and determine its prevalence and associated risk factors in Bogotá and Cali, Colombia, from 2002 to 2020. A retrospective case-control study design was employed, analyzing data from birth defect reports provided by the Program for the Prevention and Follow-up of Congenital Defects and Orphan Diseases surveillance system. Cases included live births or stillbirths with clubfoot, while controls consisted of infants without congenital abnormalities, matched in terms of birth date and hospital. Prevalence was calculated considering a 95% confidence interval using Poisson distribution, and risk factors were assessed through adjusted odds ratios obtained by logistic regression model. Of 558 255 births, 861 cases of clubfoot were identified, 48.20% were postural clubfoot, and 15 cases were syndromic clubfoot. In Bogota, prevalence rate was 15.1 per 10 000 live births, whereas in Cali it was 17.29 per 10 000 live births. Family history of clubfoot within first-degree relatives was identified as a risk factor for clubfoot. Investigating risk factors for clubfoot holds significant importance in terms of preventing and reducing morbidity within this population. Helping to drive government and healthcare initiatives aimed at providing timely and effective treatment.

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来源期刊
CiteScore
2.20
自引率
9.10%
发文量
170
审稿时长
4-8 weeks
期刊介绍: The journal highlights important recent developments from the world''s leading clinical and research institutions. The journal publishes peer-reviewed papers on the diagnosis and treatment of pediatric orthopedic disorders. It is the official journal of IFPOS (International Federation of Paediatric Orthopaedic Societies). Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool. ​
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