化脓性扁桃体炎与饮食的关系:最新进展。

Marko Belamarić, Joško Miše, Zrinka Bukvić Mokos
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引用次数: 0

摘要

化脓性扁平湿疹(Hidradenitis suppurativa,HS)是一种慢性炎症性皮肤病,以疼痛性炎症性皮损为特征,主要累及腹股沟、腋窝、乳房下和肛门生殖器等分泌腺丰富的皮肤区域,全球发病率约为 1%-4%。HS的治疗具有挑战性,需要采用各种治疗方法来控制病情。由于该病是一种慢性病,会影响患者的生活,因此许多患者都在寻求用非医疗干预措施来补充常规治疗程序的方法,其中饮食干预措施尤其受到关注。研究人员通过˝皮肤-肠道轴概念˝寻找连接肠胃系统和皮肤的方法,该概念介绍了肠胃系统微生物群与皮肤之间的密切联系。此外,饮食对胰岛素和 IGF-1(胰岛素样生长因子 1)的刺激可能会影响在 HS 发病机制中发挥作用的信号通路。患者曾尝试过各种饮食干预措施来缓解炎症和化脓症状。在已描述的不同饮食方法中,包括古法饮食、自身免疫饮食、地中海饮食和消除性饮食。膳食补充剂已成为改善 HS 临床症状和体征的主要生活方式。本综述旨在总结和介绍目前有关饮食作为 HS 可改变因素的研究结果,帮助患者浏览相关数据,并帮助他们在健康的生活方式方面做出明智的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Association Between Hidradenitis Suppurativa and Diet: An Update.

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful inflammatory lesions, predominantly affecting areas of the skin rich in apocrine glands, such as inguinal, axillary, submammary, and anogenital regions, with an estimated global prevalence between 1%-4%. The treatment of HS is challenging with various treatment modalities employed to control the disease. Since the condition is chronic and life-impairing, many patients have looked for ways to complement their conventional treatment procedures with non-medical interventions, among which dietary interventions have been of particular interest. Researchers have looked for ways to connect the gastrointestinal system with the skin through the ˝skin-gut axis concept˝ introducing a strong association between the microbiome of the gastrointestinal system and the skin. In addition, diet stimulation of insulin and IGF-1 (insulin-like growth factor 1) may impact signaling pathways playing a role in HS pathogenesis. Patients have tried various dietary interventions to alleviate their symptoms of inflammation and suppuration. Among the different dietary approaches that have been described are paleo, autoimmune, Mediterranean, and elimination diet regimes. Dietary supplements have become the mainstay of lifestyle factors aimed at improving the clinical signs and symptoms of HS. This review aims to synthesize and present the current findings on diet as a modifiable factor in HS, helping the patients to navigate through the data and helping them make informed choices on their healthy lifestyles.

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