药用乳剂：眼部给药的可行方法。

IF 1.9 4区医学 Q2 OPHTHALMOLOGY

Journal of Ocular Pharmacology and Therapeutics Pub Date : 2024-06-01 Epub Date: 2024-04-23 DOI:10.1089/jop.2023.0166

Amol Chhatrapati Bisen, Saurabh Srivastava, Anjali Mishra, Sachin Nashik Sanap, Arpon Biswas, Abhijit Deb Choudhury, Ayush Dubey, Neeraj Mohan Gupta, Karan Singh Yadav, Madhav Nilakanth Mugale, Rabi Sankar Bhatta

引用次数: 0

摘要

眼部疾病可导致严重的视力损伤和不可逆转的失明。在治疗这些威胁视力的疾病时，一般建议采用简单的局部和全身治疗方法。眼部独特的结构使眼部给药变得复杂。研究发现，眼科乳剂配方可延长药物在眼内的停留时间，改善药物通过角膜的渗透性，从而提高药物在眼内的生物利用度。因此，本研究重点介绍了适用于眼球前部和后部的眼科乳剂，同时对影响全球个人的各种眼部疾病进行了研究。本综述简要介绍了近期用于眼部给药的基于乳剂的专利创新、临床试验和上市乳剂配方，这些创新正在加强用于治疗不同眼部疾病和失调的新型眼科药物产品的开发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ocular Pharmacology and Therapeutics 医学-眼科学

CiteScore

4.60

自引率

4.30%

发文量

审稿时长

1 months

期刊介绍： Journal of Ocular Pharmacology and Therapeutics is the only peer-reviewed journal that combines the fields of ophthalmology and pharmacology to enable optimal treatment and prevention of ocular diseases and disorders. The Journal delivers the latest discoveries in the pharmacokinetics and pharmacodynamics of therapeutics for the treatment of ophthalmic disorders. Journal of Ocular Pharmacology and Therapeutics coverage includes: Glaucoma Cataracts Retinal degeneration Ocular infection, trauma, and toxicology Ocular drug delivery and biotransformation Ocular pharmacotherapy/clinical trials Ocular inflammatory and immune disorders Gene and cell-based therapies Ocular metabolic disorders Ocular ischemia and blood flow Proliferative disorders of the eye Eyes on Drug Discovery - written by Gary D. Novack, PhD, featuring the latest updates on drug and device pipeline developments as well as policy/regulatory changes by the FDA.