行走不便的脑瘫患者因神经肌肉性脊柱侧凸而进行脊柱融合术后的长期再手术率。

IF 1.6 Q3 CLINICAL NEUROLOGY
Spine deformity Pub Date : 2024-09-01 Epub Date: 2024-04-29 DOI:10.1007/s43390-024-00878-z
Christopher D Seaver, Sara J Morgan, Candice S Legister, Casey L Palmer, Eduardo C Beauchamp, Tenner J Guillaume, Walter H Truong, Steven E Koop, Joseph H Perra, John E Lonstein, Daniel J Miller
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引用次数: 0

摘要

目的:描述不行动的脑性瘫痪(CP)患者脊柱侧凸融合术后至少 10 年内再次手术的发生率以及导致手术翻修的因素:我们对在一家专科医疗中心接受初次脊柱融合术的连续非行动不便的 CP 患者进行了回顾性研究,这些患者接受初次脊柱融合术后至少 10 年(手术日期为 2001-2011 年)。再次手术的原因分为植入物失败/假关节、手术部位感染(SSI)、近端交界性脊柱后凸、植入物突出/无症状以及植入物移除。计算了每个时间间隔的再手术率及95%置信区间,并生成了精算生存曲线:144名患者符合纳入标准(平均年龄=14.3 ± 2.6岁,62.5%为男性);85.4%的患者有5年的随访数据;66.0%的患者有10年的随访数据。精算分析的估计结果表明,14.9%(95% CI:10.0-22.0)的患者在术后 5 年进行了再手术,21.7%(95% CI:15.4-30.1)的患者在术后 10 年进行了再手术。最常见的再手术原因是植入失败/假关节、SSI和植入物突出/无症状:据我们所知,这项研究是对接受脊柱融合术的不行动的CP和神经肌肉性脊柱侧凸患者进行的最大规模的长期随访。这些患者中约有22%的人在指数手术10年后需要再次手术,主要原因是植入物失败/假关节、SSI和植入物突出/无症状。并发症和再次手术在指数手术后的10年中持续存在,这就加强了在这些患者进入成年期后对其进行长期随访的必要性:证据等级:III。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term reoperation rates following spinal fusion for neuromuscular scoliosis in nonambulatory patients with cerebral palsy.

Purpose: To describe the incidence of reoperation and factors contributing to surgical revision within a minimum of 10 years after spinal fusion for scoliosis in patients with nonambulatory cerebral palsy (CP).

Methods: We conducted a retrospective review of consecutive nonambulatory patients with CP who underwent primary spinal fusion at a single specialty care center with a minimum of 10 years from their index surgery (surgery dates 2001-2011). Causes of reoperation were classified as implant failure/pseudoarthrosis, surgical site infection (SSI), proximal junctional kyphosis, prominent/symptomatic implants, and implant removal. Reoperation rates with 95% confidence intervals were calculated for each time interval, and an actuarial survival curve was generated.

Results: 144 patients met inclusion criteria (mean age = 14.3 ± 2.6 years, 62.5% male); 85.4% had 5 years follow-up data; and 66.0% had 10 years follow-up data. Estimates from the actuarial analysis suggest that 14.9% (95% CI: 10.0-22.0) underwent reoperation by 5 years postsurgery, and 21.7% (95% CI: 15.4-30.1) underwent reoperation by 10 years postsurgery. The most common causes for reoperation were implant failure/pseudoarthrosis, SSI, and prominent/symptomatic implants.

Conclusions: To our knowledge, this study is the largest long-term follow-up of nonambulatory patients with CP and neuromuscular scoliosis who underwent spinal fusion. Approximately 22% of these patients required reoperation 10 years after their index surgery, primarily due to implant failure/pseudoarthrosis, SSI, and prominent/symptomatic implants. Complications and reoperations continued throughout the 10 years period after index surgery, reinforcing the need for long-term follow-up as these patients transition into adulthood.

Level of evidence: III.

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来源期刊
CiteScore
3.20
自引率
18.80%
发文量
167
期刊介绍: Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
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