严重肥胖的 14 岁男孩,头部外伤数年后出现中枢性睡眠呼吸暂停。

IF 1 Q4 ENDOCRINOLOGY & METABOLISM
Clinical Pediatric Endocrinology Pub Date : 2024-01-01 Epub Date: 2024-02-23 DOI:10.1297/cpe.2023-0053
Yusuke Moritani, Takumi Shibazaki, Hotaru Kobori, Haruka Morota, Chizuko Nakamura, Yozo Nakazawa
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引用次数: 0

摘要

中枢性睡眠呼吸暂停(CSA)在大龄儿童中很少见。虽然中枢性睡眠呼吸暂停大多由神经系统疾病(如Chiari畸形)引起,但肥胖儿童中中枢性睡眠呼吸暂停的发生率明显更高。在此,我们描述了一个 14 岁男孩的病例,他因严重肥胖和 8 岁时的外伤性侧髓综合征病史而继发 CSA。多导睡眠监测显示他患有严重的睡眠呼吸暂停综合征,呼吸暂停-低通气指数为每小时 41.4,中枢性呼吸暂停指数为每小时 8.9。头部磁共振成像显示没有新的脑干或小脑梗塞,但小脑梗塞的旧病依然存在。肥胖主要与阻塞性睡眠呼吸暂停有关。然而,肥胖会导致咽部塌陷,胸腔容积减少导致氧气储备减少,从而抑制呼吸中枢的刺激,导致 CSA。由于头部受伤后遗症导致的呼吸中枢紊乱在急性期后有所改善,因此肥胖被认为是本病例中 CSA 的病因。因此,严重肥胖的儿童可能需要对 CSA 进行监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Severely obese 14-year-old boy with central sleep apnea several years after head trauma.

Central sleep apnea (CSA) is rare in older children. Although CSA mostly arises from neurological diseases such as Chiari malformation, the frequency of CSA is significantly higher in obese children. Herein, we describe the case of a 14-yr-old boy who presented with CSA secondary to severe obesity and a history of traumatic lateral medullary syndrome at 8 yr of age. Polysomnography revealed severe sleep apnea syndrome with apnea-hypopnea index of 41.4 per hour and central apnea index of 8.9 per hour. Magnetic resonance imaging of the head showed no new brainstem or cerebellar infarcts; however, old changes in the cerebellar infarction persisted. Obesity is primarily associated with obstructive sleep apnea. However, obesity can result in CSA through pharyngeal collapse and the reduction of oxygen reserves caused by reduced thoracic volume, which suppresses respiratory center stimulation. Because the respiratory center disorder owing to head injury sequelae improved after the acute stage, obesity was deemed the cause of CSA in this case. Hence, children with severe obesity may require CSA monitoring.

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来源期刊
Clinical Pediatric Endocrinology
Clinical Pediatric Endocrinology ENDOCRINOLOGY & METABOLISM-
CiteScore
2.40
自引率
7.10%
发文量
34
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