ThinkCancer!"--基于实践的新型癌症早期诊断干预随机可行性试验。

IF 2.5 Q2 PRIMARY HEALTH CARE
BJGP Open Pub Date : 2024-10-29 Print Date: 2024-10-01 DOI:10.3399/BJGPO.2023.0220
Stefanie Lj Disbeschl, Annie K Hendry, Alun Surgey, Daniel Walker, Nia Goulden, Bethany F Anthony, Richard Neal, Nefyn H Williams, Zoë Susannah Jane Hoare, Julia Hiscock, Rhiannon Tudor Rt Edwards, Ruth Lewis, Clare Wilkinson
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引用次数: 0

摘要

背景:英国癌症死亡人数居高不下;初级保健是早期癌症诊断的关键,因为一半可避免的延误都发生在这里。通过降低转诊门槛、更好地遵守指导原则以及改善安全网系统,可以改善这一状况。针对整个实践团队的干预措施很少。我们开发了一种新颖的全实践团队干预措施来解决这一问题。目的:测试新颖、复杂的行为干预措施 "ThinkCancer!"的可行性和可接受性,以便在随后的 III 期试验中进行评估:设计与环境:在威尔士全科诊所进行务实、优越性试点 RCT,并进行嵌入式过程评估和可行性经济分析:方法:从诊所(随机化单位)收集临床结果数据。对实践特点和癌症安全网系统进行评估。诊所员工个人填写评估和反馈表,并进行定性访谈。对干预措施进行了调整和完善:试验招募和研讨会于 2020 年 3 月至 2021 年 5 月期间进行。符合招募、干预忠实性和常规数据收集的试验进展标准。对工作人员层面的忠实性、保留和个人层面的数据收集过程进行了审查和修正。访谈强调了参与者对干预措施各个方面的积极看法。结论:"ThinkCancer!"似乎是可行的、可接受的;工作坊的新迭代已经完成,III 期试验已获得资助,以评估这种新型专业行为改变干预措施的有效性和成本效益。在多个实践中大规模开展这项活动将有可能提高其忠实度和覆盖面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
'ThinkCancer!': randomised feasibility trial of a novel practice-based early cancer diagnosis intervention.

Background: UK cancer deaths remain high; primary care is key for earlier cancer diagnosis as half of avoidable delays occur here. Improvement is possible through lower referral thresholds, better guideline adherence, and better safety-netting systems. Few interventions target whole practice teams. We developed a novel whole-practice team intervention to address this.

Aim: To test the feasibility and acceptability of a novel, complex behavioural intervention, 'ThinkCancer!', for assessment in a subsequent Phase III trial.

Design & setting: Pragmatic, superiority pilot randomised controlled trial (RCT) with an embedded process evaluation and feasibility economic analysis in Welsh general practices.

Method: Clinical outcome data were collected from practices (the unit of randomisation). Practice characteristics and cancer safety-netting systems were assessed. Individual practice staff completed evaluation and feedback forms and qualitative interviews. The intervention was adapted and refined.

Results: Trial recruitment and workshop deliveries took place between March 2020 and May 2021. Trial progression criteria for recruitment, intervention fidelity, and routine data collection were met. Staff-level fidelity, retention, and individual level data collection processes were reviewed and amended. Interviews highlighted positive participant views on all aspects of the intervention. All practices set out to liberalise referral thresholds appropriately, implement guidelines, and address safety-netting plans in detail.

Conclusion: 'ThinkCancer!' appears feasible and acceptable. The new iteration of the workshops was completed and the Phase III trial has been funded to assess the effectiveness and cost-effectiveness of this novel professional behaviour change intervention. Delivery at scale to multiple practices will likely improve fidelity and reach.

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来源期刊
BJGP Open
BJGP Open Medicine-Family Practice
CiteScore
5.00
自引率
0.00%
发文量
181
审稿时长
22 weeks
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