A Multiple Lines of Evidence Approach to Demonstrate Effectiveness of PFAS Remediation Technologies

Significant investments have been made to develop treatment technologies, particularly destructive approaches, for a variety of per- and polyfluoroalkyl substances (PFAS) that are present in groundwater, surface water, and other environmental media. A multiple lines of evidence approach were developed to assist regulators, funding agencies, and practitioners in evaluating PFAS treatment technology performance. This article describes each of three lines of evidence that a technology is effective: (1) decrease in target PFAS concentrations is observed; (2) PFAS treatment transformation products are identified and quantified; and (3) a treatment mechanism is proposed that is consistent with previous studies and supported by data. Other considerations are also described to inform conclusions about knowledge gaps and priorities for future testing. Collectively, these lines of evidence and other considerations help communicate the complexities of PFAS treatment, strengthen research plans, standardize technology evaluator reviews, and inform realistic expectations of PFAS treatment technologies.