肾素瘤和肾外生肾素肿瘤患者的诊断难题

IF 3 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Clinical Endocrinology Pub Date : 2024-05-02 DOI:10.1111/cen.15069

Botond Fabian, Oskar Ragnarsson, Aleksandar Prazic, Mikael Rydén, Cristina Volpe, Ola Lindgren

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引用次数: 0

摘要

分泌肾素的肿瘤是继发性高血压和低钾血症的罕见病因。这些肿瘤通常可以通过手术治愈，因此正确的诊断和肿瘤定位至关重要。在本文中，我们介绍了最近确诊为肾素分泌性肿瘤的三名瑞典患者，其中两名是肾素瘤患者，一名是肾外肾素分泌性肿瘤患者，以说明诊断方面的挑战。我们还讨论了生化检查、不同成像技术（计算机断层扫描[CT]、磁共振成像和[18F]氟脱氧葡萄糖正电子发射断层扫描-CT）的利弊，以及肾静脉取样（RVC）如何有助于肿瘤定位。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Diagnostic challenges in patients with reninomas and extrarenal renin-producing tumours

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Diagnostic challenges in patients with reninomas and extrarenal renin-producing tumours

Renin-secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work-up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin-producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work-up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose-positron emission tomography-CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.

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来源期刊

Clinical Endocrinology 医学-内分泌学与代谢

CiteScore

6.40

自引率

3.10%

发文量

192

审稿时长

1 months

期刊介绍： Clinical Endocrinology publishes papers and reviews which focus on the clinical aspects of endocrinology, including the clinical application of molecular endocrinology. It does not publish papers relating directly to diabetes care and clinical management. It features reviews, original papers, commentaries, correspondence and Clinical Questions. Clinical Endocrinology is essential reading not only for those engaged in endocrinological research but also for those involved primarily in clinical practice.