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芳香胺作用下 5-(Het)芳基-4-(三氟甲基)呋喃-2,3-二酮再环化产物的合成及其抗菌和镇痛活性

IF 0.8 4区 化学 Q4 CHEMISTRY, ORGANIC
Russian Journal of Organic Chemistry Pub Date : 2024-04-29 DOI:10.1134/S1070428024020064
E. P. Kozlova, S. Y. Balandina, R. R. Makhmudov, N. Y. Lisovenko
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引用次数: 0

摘要

摘要4-取代的5-羟基-5-(三氟甲基)二氢呋喃-2,3-二酮是由5-取代的4,4,4-三氟乙酰基呋喃-2,3-二酮与芳香胺反应合成的。合成的化合物具有抗菌和抗痛觉活性。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis and Antimicrobial and Analgesic Activity of Products of the Recyclization of 5-(Het)Aryl-4-(trifluoromethyl)furan-2,3-diones under the Action of Aromatic Amines

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Synthesis and Antimicrobial and Analgesic Activity of Products of the Recyclization of 5-(Het)Aryl-4-(trifluoromethyl)furan-2,3-diones under the Action of Aromatic Amines

4-Substituted 5-hydroxy-5-(trifluoromethyl)dihydrofuran-2,3-diones were synthesized by the reaction of 5-substituted 4,4,4-trifluoroacetylfuran-2,3-diones with aromatic amines. The synthesized compounds exhibited the antibacterial and antinociceptive activity.

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来源期刊
Russian Journal of Organic Chemistry
Russian Journal of Organic Chemistry 化学-有机化学
CiteScore
1.40
自引率
25.00%
发文量
139
审稿时长
3-6 weeks
期刊介绍： Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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