估算概念的发展现状

IF 1.3 4区医学 Q4 PHARMACOLOGY & PHARMACY

Pharmaceutical Statistics Pub Date : 2024-04-27 DOI:10.1002/pst.2395

Alexander Fierenz, Antonia Zapf

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引用次数: 0

摘要

自从在治疗学研究中引入估测概念以来，已经开发出了几种适应方案。这篇短文强调了估测概念的重要方面。通过文献研究，确定了这一框架的不同扩展。文章介绍了针对并发症的不同修改策略，并举例说明了在临床研究中实施估计值的方法。文章反映出，instimand 是一个有待进一步探索的持续研究领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Current developments of the estimand concept

Since the introduction of the estimand in therapeutical studies, several adaptions have been developed. This short article highlights the important aspects of the estimand concept. A literature research was conducted to identify different extensions to this framework. Different modified strategies for intercurrent events are presented, as well as examples of methods to implement the estimand in clinical studies. The article reflects that the estimand is an ongoing research field with further exploration.

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来源期刊

Pharmaceutical Statistics 医学-统计学与概率论

CiteScore

2.70

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Pharmaceutical Statistics is an industry-led initiative, tackling real problems in statistical applications. The Journal publishes papers that share experiences in the practical application of statistics within the pharmaceutical industry. It covers all aspects of pharmaceutical statistical applications from discovery, through pre-clinical development, clinical development, post-marketing surveillance, consumer health, production, epidemiology, and health economics. The Journal is both international and multidisciplinary. It includes high quality practical papers, case studies and review papers.