Prospero Homeobox-1 (PROX-1) 对肝细胞癌细胞致癌表型的影响

IF 2.6 4区医学 Q2 GENETICS & HEREDITY

Cancer Genomics & Proteomics Pub Date : 2024-04-27 DOI:10.21873/cgp.20448

Ji-Yun Hong, Sun-Young Park, Young-Lan Park, Ga-Ram You, Jae Hyun Yoon, Young-Eun Joo, Sung Kyu Choi, Sung-Bum Cho

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引用次数: 0

摘要

转录因子prospero homeobox-1（PROX-1）对各种器官的胚胎发育和细胞命运的规范至关重要。根据癌症类型的不同，它具有致癌或抑制肿瘤的活性。然而，PROX-1 与肝细胞癌（HCC）之间的关系仍然模糊不清。本研究旨在探讨 PROX-1 对人类 HCC 细胞侵袭性和致癌表型的影响。

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Impact of Prospero Homeobox-1 (PROX-1) οn the Oncogenic Phenotypes of Hepatocellular Carcinoma Cells.

Transcriptional factor prospero homeobox-1 (PROX-1) is crucial for the embryonic development of various organs and cell fate specification. It exhibits either an oncogenic or tumor suppressive activity depending on cancer types. However, the relationship between PROX-1 and hepatocellular carcinoma (HCC) remains obscure. This study was conducted to investigate the effect of PROX-1 on the invasive and oncogenic phenotypes of human HCC cells.

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来源期刊

Cancer Genomics & Proteomics ONCOLOGY-GENETICS & HEREDITY

CiteScore

5.00

自引率

8.00%

发文量

期刊介绍： Cancer Genomics & Proteomics (CGP) is an international peer-reviewed journal designed to publish rapidly high quality articles and reviews on the application of genomic and proteomic technology to basic, experimental and clinical cancer research. In this site you may find information concerning the editorial board, editorial policy, issue contents, subscriptions, submission of manuscripts and advertising. The first issue of CGP circulated in January 2004. Cancer Genomics & Proteomics is a journal of the International Institute of Anticancer Research. From January 2013 CGP is converted to an online-only open access journal. Cancer Genomics & Proteomics supports (a) the aims and the research projects of the INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH and (b) the organization of the INTERNATIONAL CONFERENCES OF ANTICANCER RESEARCH.