近视马来学童的角膜特征及其与轴长的关系

Syarifah Faiza Syed Mohd Dardin, B. Mohd-Ali, Mizhanim Mohamad Shahimin, Mohd Norhafizun Mohd Saman, N. Mohidin
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摘要

引言 每只眼睛的角膜特征都是独一无二的,在不同程度的屈光不正中,角膜特征也会有所不同。然而,关于马来近视学童的角膜特征(包括低度近视组和中度近视组之间的差异)的文献数据极少。因此,本研究旨在确定马来近视学童的角膜特征及其与轴长的关系。方法 从 42 名近视的马来学童中提取了 84 个数据样本。使用非接触式光学生物测量仪 Lenstar LS900 测量了中央角膜厚度 (CCT)、角膜曲率、角膜直径和轴长。随后将数据按球面等效屈光度(SER)分为低度近视组和中度近视组,并采用配对 t 检验确定两组之间角膜特征的差异。进行单变量和多变量线性回归,以确定与轴长显著相关的因素。结果 低度近视组和中度近视组的 CCT、角膜曲率和角膜直径分别无明显差异(t82=0.015,P=0.99)、(t82=-0.802,P=0.43)和(t82=-0.575,P=0.57)。Pearson单变量相关分析发现,轴长与角膜曲率(r=-0.765,P<0.001)和角膜直径(r=0.614,P<0.001)显著相关,但与CCT(r=0.046,P=0.68)无显著相关。多元回归分析表明,轴长与角膜曲率较平(P<0.001)、年龄较大(P<0.001)和角膜直径较大(P=0.02)明显相关。结论 本研究报告了马来近视学童的角膜特征及其与轴长的关系。研究结果可作为马来近视学童群体的参考值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Corneal Characteristics of Myopic Malay School Children and Their Association with Axial Length
Introduction Corneal characteristics are unique to each eye and can vary among different levels of refractive errors. However, minimal data are available in the literature on corneal characteristics in myopic Malay school children including the difference between the low myopic group and the moderate myopic group. Therefore, this study aims to determine the corneal characteristics of myopic Malay school children and their associations with axial length. Methods A total of eighty-four data samples were extracted from forty-two myopic Malay school children. Measurements of the central corneal thickness (CCT), corneal curvature, corneal diameter, and axial length were measured using Lenstar LS900, a non-contact optical biometer. Data were later stratified by the spherical equivalent refraction (SER) into a low myopic group and a moderate myopic group, and paired t-test were employed to determine the differences in the corneal characteristics between these two groups. Univariate and multivariate linear regressions were performed to identify factors that are significantly associated with axial length. Results There was no significant difference in the CCT, corneal curvature and corneal diameter between the low myopic group and the moderate myopic group (t82=0.015, P=0.99), (t82=−0.802, P=0.43) and (t82=−0.575, P=0.57), respectively. Pearson univariate correlation analysis found that axial length significantly correlated with corneal curvature (r=−0.765, P<0.001) and corneal diameter (r=0.614, P<0.001) but no significant correlation found with CCT (r=0.046, P=0.68). Multiple regression analysis showed that axial length was significantly associated with a flatter corneal curvature (P<0.001), older age (P<0.001) and larger corneal diameter (P=0.02). Conclusion This study reported the corneal characteristics in myopic Malay school children and its associations with axial length. Results of this study can serve as a reference value for the myopic Malay schoolchild population.
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