阴道拭子和宫颈拭子在治疗顽固性和复发性生殖道感染 (RTI) 中的重要微生物学作用

Heba E. Hashem, Z. H. Ibrahim, Adel M. Nada, Wafaa O. Ahmed, Heba Ezzat
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摘要

背景:生殖道感染(RTI)是一种常见疾病,如果不及时治疗,可导致严重的健康问题,如不孕症和新生儿感染。研究目的本研究旨在确定生殖年龄妇女中 RTI 的风险因素、人口统计学、致病病原体和患病率。研究对象和方法:在妇幼保健诊所就诊的妇女中开展了一项前瞻性研究。研究人员对阴道/宫颈拭子进行了检查,检索了相关数据,然后进行了统计分析。研究共纳入 295 名妇女,中位年龄为 25.2 岁。研究结果研究期间,84%的患者已婚。总体而言,42%的病例有阴道毛滴虫感染,23%有淋病奈瑟菌感染,18%有细菌性阴道病,9%有念珠菌感染,22%有症状的病例菌群生长正常。尽管混合性阴道感染的真实发生率可能更高,但据报告只有 15.6%的病例患有混合性阴道感染。已婚妇女经常患有 RTI,其中许多人还使用宫内节育器。结论在中东国家,RTI 在已婚妇女中非常普遍。淋病奈瑟菌和阴道毛滴虫是本次研究中最常发现的细菌。研究表明,症状与实验室确诊的某些感染类型之间的相关性很低。这强调了实验室检测作为准确诊断 RTI 的关键诊断工具的重要性,并突出了仅凭临床判断诊断 RTI 的难度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Valuable Microbiological Role of Vaginal and Cervical Swabs in The Management of Persistent and Recurrent Reproductive Tract Infections (RTIs)
Background: Reproductive tract infections (RTIs) are a frequent medical condition that can lead to serious health issues such as infertility and newborn infections if it is not treated promptly. Objective: This study aimed to determine the risk factors, demography, causative pathogens, and prevalence of RTI in women who are reproductively aged. Subjects and methods: A prospective study was conducted among women who attended Maternal-Child Health Clinics. Vaginal/cervical swabs were examined, and relevant data were retrieved and then statistically analyzed. 295 women were included in the study with a median age of 25.2 years. Results: At the time of the study, 84% of the patients were married. Overall, 42% of cases had Trichomonas vaginalis , 23% had Neisseria gonorrhea, 18% had bacterial vaginosis, 9% had Candida infection, and 22% of cases with symptoms had normal flora growth. Although the true frequency of mixed vaginal infections may be higher, only 15.6% of cases were reported to have them. Married women frequently had RTIs, and many of them also used IUDs. Conclusion: In Middle Eastern nations, RTIs are highly prevalent among married women. Neisseria gonorrhea and Trichomonas vaginalis were the most frequently found bacteria in the current study. It has been shown that there was a poor correlation between the symptoms and certain types of laboratory-confirmed infections. This underlines the significance of laboratory testing as a key diagnostic tool for accurate RTI diagnosis and highlights the difficulty of diagnosing RTIs based solely on clinical judgment.
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