对比增强磁共振引导的上腹部肿瘤适应性放疗的可行性和安全性:初步探索

IF 3.4 Q2 ONCOLOGY
Wenheng Jiang , Xihua Shi , Xiang Zhang , Zhenjiang Li , Jinbo Yue
{"title":"对比增强磁共振引导的上腹部肿瘤适应性放疗的可行性和安全性:初步探索","authors":"Wenheng Jiang ,&nbsp;Xihua Shi ,&nbsp;Xiang Zhang ,&nbsp;Zhenjiang Li ,&nbsp;Jinbo Yue","doi":"10.1016/j.phro.2024.100582","DOIUrl":null,"url":null,"abstract":"<div><p>This study investigates the use of contrast-enhanced magnetic resonance (MR) in MR-guided adaptive radiotherapy (MRgART) for upper abdominal tumors. Contrast-enhanced T1-weighted MR (cT1w MR) using half doses of gadoterate was used to guide daily adaptive radiotherapy for tumors poorly visualized without contrast. The use of gadoterate was found to be feasible and safe in 5-fraction MRgART and could improve the contrast-to-noise ratio of MR images. And the use of cT1w MR could reduce the interobserver variation of adaptive tumor delineation compared to plain T1w MR (4.41 vs. 6.58, p &lt; 0.001) and T2w MR (4.41 vs. 7.42, p &lt; 0.001).</p></div>","PeriodicalId":36850,"journal":{"name":"Physics and Imaging in Radiation Oncology","volume":"30 ","pages":"Article 100582"},"PeriodicalIF":3.4000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405631624000526/pdfft?md5=d282df7dcb80fe0f3096017be000b790&pid=1-s2.0-S2405631624000526-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Feasibility and safety of contrast-enhanced magnetic resonance-guided adaptive radiotherapy for upper abdominal tumors: A preliminary exploration\",\"authors\":\"Wenheng Jiang ,&nbsp;Xihua Shi ,&nbsp;Xiang Zhang ,&nbsp;Zhenjiang Li ,&nbsp;Jinbo Yue\",\"doi\":\"10.1016/j.phro.2024.100582\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This study investigates the use of contrast-enhanced magnetic resonance (MR) in MR-guided adaptive radiotherapy (MRgART) for upper abdominal tumors. Contrast-enhanced T1-weighted MR (cT1w MR) using half doses of gadoterate was used to guide daily adaptive radiotherapy for tumors poorly visualized without contrast. The use of gadoterate was found to be feasible and safe in 5-fraction MRgART and could improve the contrast-to-noise ratio of MR images. And the use of cT1w MR could reduce the interobserver variation of adaptive tumor delineation compared to plain T1w MR (4.41 vs. 6.58, p &lt; 0.001) and T2w MR (4.41 vs. 7.42, p &lt; 0.001).</p></div>\",\"PeriodicalId\":36850,\"journal\":{\"name\":\"Physics and Imaging in Radiation Oncology\",\"volume\":\"30 \",\"pages\":\"Article 100582\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2405631624000526/pdfft?md5=d282df7dcb80fe0f3096017be000b790&pid=1-s2.0-S2405631624000526-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics and Imaging in Radiation Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2405631624000526\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics and Imaging in Radiation Oncology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405631624000526","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

本研究探讨了造影剂增强磁共振(MR)在磁共振引导的上腹部肿瘤自适应放疗(MRgART)中的应用。使用半剂量的钆喷酸来进行对比增强 T1 加权磁共振(cT1w MR),以指导日常自适应放疗,用于治疗无对比剂情况下可视性差的肿瘤。研究发现,在 5 分 MRgART 中使用钆喷酸是可行和安全的,并能提高 MR 图像的对比度-噪声比。与普通 T1w MR(4.41 vs. 6.58,p < 0.001)和 T2w MR(4.41 vs. 7.42,p < 0.001)相比,使用 cT1w MR 可减少自适应肿瘤分界的观察者间差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility and safety of contrast-enhanced magnetic resonance-guided adaptive radiotherapy for upper abdominal tumors: A preliminary exploration

This study investigates the use of contrast-enhanced magnetic resonance (MR) in MR-guided adaptive radiotherapy (MRgART) for upper abdominal tumors. Contrast-enhanced T1-weighted MR (cT1w MR) using half doses of gadoterate was used to guide daily adaptive radiotherapy for tumors poorly visualized without contrast. The use of gadoterate was found to be feasible and safe in 5-fraction MRgART and could improve the contrast-to-noise ratio of MR images. And the use of cT1w MR could reduce the interobserver variation of adaptive tumor delineation compared to plain T1w MR (4.41 vs. 6.58, p < 0.001) and T2w MR (4.41 vs. 7.42, p < 0.001).

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Physics and Imaging in Radiation Oncology
Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation
CiteScore
5.30
自引率
18.90%
发文量
93
审稿时长
6 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信