生殖器溃疡病:研究当前流行病的相关因素和快速诊断方法的实用性

Dhanashree P. Inamdar, Arun Kulkarni, Anuradha Basavaraju
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引用次数: 0

摘要

摘要 生殖器溃疡病(GUD)被认为是临床医生最棘手的难题,因为有效而快速的诊断方法有限,尤其是在印度。个人的性行为在 GUD 的致病过程中起着一定的作用,它取决于心理、行为和社会福祉,而这些因素在 COVID-19 大流行期间受到了严重影响。因此,本研究采用简单、快速的微生物学方法来确定生殖器溃疡的病因,并研究与之相关的各种因素。 在为期一年的研究期间,对 71 名疑似生殖器溃疡患者进行了各种快速检测,如染色法(Giemsa、革兰氏和 Diff Quick)和血清学抗体检测,以诊断引起生殖器溃疡的病原体。在获得知情同意后,研究人员在表格中记录并分析了社会人口学和行为学因素。 47.9%的生殖器溃疡病例可通过快速检测确诊。所有测试的周转时间均少于 60 分钟。生殖器疱疹是最常见的 GUD,其次是梅毒。大多数 GUD 患者为男性(74.6%)、34 岁以上(62%)、识字(71.8%)和有收入(70.4%)。与熟人发生滥交(83.1%)等行为因素与 GUD 有显著关联(P 0.04)。 快速诊断检测有助于对 GUD 病例进行早期治疗。在我们的研究中,在 COVID-19 大流行期间,识字率、经济独立和与熟人滥交等因素与 GUD 相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genital ulcer disease: Study of factors associated and utility of rapid diagnostic methods in current pandemic
ABSTRACT Genital ulcer disease (GUD) is regarded as the most difficult conundrum for clinicians, as valid and rapid methods to diagnose them are limited, especially in India. The sexual behavior of an individual plays a role in the causation of GUD, and it depends on psychological, behavioral, and social well-being, which was significantly affected during the COVID-19 pandemic. Hence, the present study was undertaken to determine the etiology of genital ulcers by using simple, rapid microbiological methods and to study various factors associated with them. Various rapid tests like staining (Giemsa, Gram, and Diff Quick) and serology for antibody detection were used to diagnose agents causing genital ulcers among 71 suspected patients during the study period of 1 year. After due informed consent, sociodemographic and behavioral factors were recorded in proforma and analyzed. Rapid tests could aid in diagnosing 47.9% of cases of GUD. Turnaround time was less than 60 minutes for all tests carried out. Genital herpes was the most common GUD followed by syphilis. Male gender (74.6%), age group of more than 34 years old (62%), literate (71.8%), and earning (70.4%) constituted most of the population presenting with GUD. Behavioral factors like promiscuity with a known person (83.1%) had a significant association (P 0.04) with GUD. Rapid diagnostic tests could assist in the early treatment of GUD cases. Factors like literacy, financial independence, and promiscuity with known individuals were associated with GUD in our study during the COVID-19 pandemic.
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