[加泰罗尼亚骨折联络服务的成本效益分析]。

IF 1.1 Q4 HEALTH CARE SCIENCES & SERVICES
X. Surís , M.J. Pueyo-Sánchez , A. Ricart , A. Naranjo , T. Casanova , C. Gómez-Vaquero , E. Duaso , J.M. Cancio-Trujillo , J. Sánchez-Martín , A. Pérez-Mitru
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引用次数: 0

摘要

方法通过马尔可夫模型进行成本效用评估,该模型模拟了脆性骨折后启动抗骨质疏松治疗的候选患者队列的疾病进展情况。该模型的时间跨度为 10 年,每个周期的持续时间为 6 个月。临床、经济学和生活质量参数均来自文献,并从四项加泰罗尼亚脆性骨折研究中得出。研究采用了加泰罗尼亚医疗服务视角,考虑了以 2022 欧元表示的直接医疗成本。对成本和结果采用了 3% 的贴现率。结果与标准治疗相比,FLS 将促进抗骨质疏松治疗的启动和持续,降低与后续脆性骨折相关的发病率和死亡率。据估计,每位患者的临床获益增量为 0.055 年和 0.112 个质量调整生命年(QALYs)。据估计,每名患者的成本较高(1,073.79 欧元),因此每获得 1 QALYs 的增量成本效用比为 9,602.72 欧元。结论从加泰罗尼亚医疗服务的角度来看,在 FF 二级预防中引入 FLS 是一项具有成本效益的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Análisis de coste-efectividad de las Unidades de Coordinación de Fracturas en Cataluña

Objective

To assess the cost-effectiveness of Fracture Liaison Service (FLS) compared to the standard of care for secondary prevention of fragility fractures form the perspective of the Catalan Health Service.

Methods

Cost-utility assessment through a Markov model that simulated disease progression of a patients’ cohort candidates to initiate antiosteoporotic treatment after a fragility fracture. A time horizon of 10 years and a 6-month duration per cycle was established. Clinical, economics and quality of life parameters were obtained from the literature and derived from four Catalan FLS. The Catalan Health Service perspective was adopted, considering direct health costs expressed in 2022 euros. A 3% discount rate was applied on costs and outcomes. Uncertainty was assessed through multiple sensitivity analyses.

Results

Compared to the standard of care, FLS would promote antiosteoporotic initiation and persistence, reducing the incidence and mortality associated with subsequent fragility fractures. This incremental clinical benefit was estimated at 0.055 years and 0.112 quality-adjusted life years (QALYs) per patient. A higher cost (€1,073.79 per patient) was estimated, resulting into an incremental cost-utility ratio of €9,602.72 per QALYs gained. The sensitivity analyses performed were consistent, corroborating the robustness and conservative approach of the base-case.

Conclusions

The introduction of FLS for the secondary prevention of FF would represent a cost-effective strategy from the Catalan Health Service perspective.

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来源期刊
CiteScore
1.70
自引率
8.30%
发文量
83
审稿时长
57 days
期刊介绍: Revista de Calidad Asistencial (Quality Healthcare) (RCA) is the official Journal of the Spanish Society of Quality Healthcare (Sociedad Española de Calidad Asistencial) (SECA) and is a tool for the dissemination of knowledge and reflection for the quality management of health services in Primary Care, as well as in Hospitals. It publishes articles associated with any aspect of research in the field of public health and health administration, including health education, epidemiology, medical statistics, health information, health economics, quality management, and health policies. The Journal publishes 6 issues, exclusively in electronic format. The Journal publishes, in Spanish, Original works, Special and Review Articles, as well as other sections. Articles are subjected to a rigorous, double blind, review process (peer review)
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