经颅多普勒搏动指数与脑静脉窦血栓患者临床预后的相关性研究

Kshitij Bansal, V. Sardana, Bharat Bhushan, Dilip Maheshwari
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引用次数: 0

摘要

背景:脑静脉血栓(CVT)占脑卒中的 3%,可通过无创经颅多普勒(TCD)超声波实时测量脑血管功能。TCD 导出的搏动指数 (PI) 与颅内压 (ICP) 高度相关,是一种可靠的无创监测工具。目的:本研究旨在将 TCD 的搏动指数与 CVT 患者的临床预后相关联。方法:MBS 医院神经内科对 2022 年 6 月至 2022 年 12 月期间收治的 41 名 CVT 患者进行了前瞻性观察研究。每位患者都接受了 TCD 检查,并记录了 PI。研究结果使用 SPSS 进行分析。结果:在 41 名患者中,2 人死亡,39 人出院。入院时左侧大脑中动脉(MCA)的PI在出院患者中为1.19 ± 0.20,在死亡患者中为1.64 ± 0.10 ( p = .003)。同样,入院时右侧 MCA 的 PI 在出院者中为 1.23 ± 0.21,在死亡者中为 1.63 ± 0.20 ( p = .02)。此外,左侧和右侧 MCA 的 PI 与入院时的 CVT GS 评分呈显著正相关(r = 0.70,p < .05;r = 0.64,p < .05)。结论在住院期间死亡的患者中,入院时左右MCA的PI均明显升高。此外,PI 与就诊时的 CVT GS 评分明显相关。因此,入院时通过 TCD 测定的 PI 可以预测 CVT 患者的临床预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Study of the Correlation of Pulsatility Index by Transcranial Doppler in the Clinical Outcome of Patients with Cerebral Venous Sinus 
Thrombosis
Background: Cerebral Venous Thrombosis (CVT), accounting for 3% of strokes, can be assessed using non-invasive Transcranial Doppler (TCD) ultrasound to measure cerebrovascular function in real-time. The TCD-derived pulsatility index (PI), highly correlates with intracranial pressure (ICP) and serves as a reliable non-invasive monitoring tool. Aim: This study aims to correlate PI by TCD with clinical outcomes in CVT patients. Methods: A prospective observational study of 41 CVT patients admitted between June 2022 to December 2022 was conducted in the Department of Neurology of MBS Hospital. Each patient was subjected to TCD and the PI was also recorded. The results were analysed with SPSS. Results: Out of the 41 patients, two patients died and 39 patients were discharged. The PI at admission in the left middle cerebral artery (MCA) was 1.19 ± 0.20 amongst discharged and 1.64 ± 0.10 amongst those who died ( p = .003). Similarly, the PI at admission in the right MCA was 1.23 ± 0.21 amongst those discharged and 1.63 ± 0.20 amongst those who died ( p = .02). Also, PI in both left and right MCA positively and significantly correlated with CVT GS score at admission (r = 0.70, p < .05; r = 0.64, p < .05). Conclusion: PI at admission is both right and left MCA was found to be significantly higher in patients who died during the hospital stay. Also, PI significantly correlated with the CVT GS score at the presentation. Thus, PI at admission by TCD can predict the clinical outcome of patients with CVT.
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