S. Dugheri, G. Cappelli, N. Mucci, Giulio Arcangeli, Lucia Isolani, L. Trevisani, Donato Squillaci, Elisabetta Bucaletti, Jacopo Ceccarelli, Simone Pettinari, Giovanni Amagliani, Niccolò Fanfani
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引用次数: 0
摘要
甲醛(FA)是一种危险化学品,在解剖病理实验室中使用率很高。与 FA 职业接触有关的不良健康影响通常与长期接触有关,但短期接触峰值浓度同样值得高度关注。职业监测通常使用 8 小时时间重量平均值(TWA)指标来评估接触情况,但对于具有急性影响的化学品,强烈建议使用 15 分钟的短期接触指标。在本研究中,职业监测是在解剖病理学实验室中进行的,使用的是连续、瞬时和直读仪器,共进行了 65 个工作班(WS)。在这些工作班次中,没有一个超过欧盟(EU)的 FA TWA 职业限值(620 g/m3)。不同的是,有 40 个工作班超过了欧盟短期接触限值 (STEL)(740 g/m3),甚至一个工作班多次超标。有鉴于此,8 小时 TWA 指标只能提供有关峰值排放的暴露情景的少量信息,而通过连续监测进行的 15 分钟峰值暴露评估则有助于管理风险。此外,利用推论方程,建议 FA 采用 8 小时 TWA 的行动值 (AV),超过该值则强烈建议进行 15 分钟测量,该值等于 23.1 g/m3 。
Strategy to evaluate the impact of formaldehyde in anatomical pathology laboratory part II
Formaldehyde (FA) is a hazardous chemical, highly used in the anatomical pathology laboratories. The adverse health effects related to FA occupational exposure are generally related to long-term exposure, however the short-term exposure to peak concentrations are equally of high concern. The occupational monitoring commonly uses the 8h-Time Weight Average (TWA) metric to assess the exposure, but for those chemicals with acute effects, also the15min short-term exposure is strongly recommended. In this study, the occupational monitoring was carried out in an anatomical pathology laboratory with an in-continuous, instantaneous, and direct reading instrument for 65 work shifts (WS). In none of these, the FA European Union (EU) TWA occupational limit (620 g/m3) was exceeded. Differently, in 40 WS the EU Short Term Exposure Limit (STEL) (740 g/m3) was exceeded, even several times a WS. In sight of this, the 8h-TWA metric only could give poor information of the exposure scenario, involving peak emissions, then a 15min peak exposure assessment, via in continuous monitoring, could help managing the risk. In addition, using the inference equation, an Action Value (AV) of the 8h-TWA above which the 15min measurements are strongly recommended, equal to 23.1 g/m3, is suggested for FA.