2023 年刚果共和国(布拉柴维尔)爆发急性肠道传染病期间传染病专家和 Rospotrebnadzor 流行病学家的工作成果

N. Pshenichnaya, E. V. Naidenova, G. V. Gopatsa, D. A. Kuznetsova, L. N. Dmitrieva, A. V. Evteev, A. A. Tushinsky, S. A. Portenko, N. Obissa, M. Mpompolo, Sh. L. Elenga-Bongo, M. Inana, J.-C. Mobousse Misse, V. V. Kutyrev, V. Smolensky
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引用次数: 0

摘要

本文分析了俄罗斯和刚果传染病专家及流行病学家为破译 2023 年夏季多利西(刚果共和国)爆发肠道传染病的病因和原因而联合开展的工作的结果。研究发现,肠道传染病发病率上升主要是由伤寒和痢疾病原体引起的;热带疟疾是一种综合病理现象。没有发现霍乱病例。供水系统失灵、家庭失修以及公众对预防肠道感染的认识不足导致病原体传播活跃。疫情过程的综合表现证明了疫情的水生性质。此外,还记录了病原体通过家庭接触途径传播的病例,不排除食物传播的可能性。伤寒和志贺菌病的重症和并发症患者占住院患者的 50%。患者就医延迟。现有的抗菌治疗方案效果不佳,因为无法通过确定对药物的敏感性来进行实验室确诊。不加控制的治疗助长了病原体抗生素耐药性的产生、细菌释放时间的延长以及随后感染的扩散。Rospotrebnadzor 的传染病专家和流行病学家向刚果同事提供了咨询和实际援助,制定并提出了优化抗流行病和治疗措施的建议,同时考虑到了对爆发和发展原因的评估结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Results of Work of Infectious Disease Specialists and Epidemiologists of the Rospotrebnadzor during the Outbreak of Acute Intestinal Infections in the Republic of the Congo (Brazzaville) in 2023
This paper provides an analysis of the results of joint work of Russian and Congolese infectious disease specialists and epidemiologists to decipher the etiology and causes of the outbreak of intestinal infections in Dolisie (Republic of the Congo) in the summer of 2023. It has been found that the increase in the incidence of intestinal infections was caused mainly by the agents of typhoid fever and dysentery; tropical malaria was a combined pathology. No cases of cholera patient detection were registered. Failure of water supply system, domestic disrepair, and low public awareness about prevention of intestinal infections contributed to the active transmission of pathogens. The combination of epidemic process manifestations testified to the aquatic nature of the outbreak. Also, cases of pathogen transmission through contact household route were recorded, food transmission was not excluded. Patients with severe and complicated forms of typhoid fever and shigellosis accounted for 50 % of those hospitalized. There was delay in seeking medical care. The available regimens of antibacterial therapy were ineffective, since there was no possibility of laboratory confirmation of the diagnosis with determination of sensitivity to drugs. Uncontrolled treatment facilitated the emergence of antibiotic resistance in pathogens, prolonged bacterial release and subsequent spread of infection. Infectious disease specialists and epidemiologists of the Rospotrebnadzor provided consulting and practical assistance to Congolese colleagues, developed and presented recommendations for optimizing anti-epidemic and therapeutic measures, taking into account the results of assessment of the causes for onset and development of the outbreak.
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