研究 Launaea angustifolia 提取物对雌性大鼠生殖功能的影响

IF 0.4 4区 农林科学 Q4 AGRICULTURE, DAIRY & ANIMAL SCIENCE
A. Ammari, A. Alhimaidi, R. Amran, Ahmed G. Rady
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引用次数: 0

摘要

研究背景本研究旨在通过化学筛选法研究 Launaea angustifolia 甲醇提取物对雌性大鼠生殖器官的影响。研究方法:将二十五只雌性大鼠分成五个不同的组进行研究。对照组不服用任何剂量,阴性对照组口服 DEMSO。第 10 组每天按每公斤体重摄入 10 毫克,第 50 组每天按每公斤体重摄入 50 毫克,第 100 组每天按每公斤体重摄入 100 毫克,为期两周。结果:尽管在调查过程中雌性大鼠的体重有所上升,但给药 14 天后,各组之间并无明显差异。就雌性大鼠而言,除第 1 天和第 3 天外,对照组的体重在所有实验日都明显高于服用 50 毫克和 100 毫克的组别(P 小于 0.05)。虽然对照组的卵巢重量比暴露于二甲基亚砜的组有明显的增加,但对照组的卵巢重量比暴露于二甲基亚砜的组有明显的增加(P<0.05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Investigating the Impact of Launaea angustifolia Extract on the Reproduction Function of Female Rats
Background: The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening. Methods: A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks. Result: Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P less than 0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.
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来源期刊
Indian Journal of Animal Research
Indian Journal of Animal Research AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
1.00
自引率
20.00%
发文量
332
审稿时长
6 months
期刊介绍: The IJAR, the flagship print journal of ARCC, it is a monthly journal published without any break since 1966. The overall aim of the journal is to promote the professional development of its readers, researchers and scientists around the world. Indian Journal of Animal Research is peer-reviewed journal and has gained recognition for its high standard in the academic world. It anatomy, nutrition, production, management, veterinary, fisheries, zoology etc. The objective of the journal is to provide a forum to the scientific community to publish their research findings and also to open new vistas for further research. The journal is being covered under international indexing and abstracting services.
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