{"title":"研究 Launaea angustifolia 提取物对雌性大鼠生殖功能的影响","authors":"A. Ammari, A. Alhimaidi, R. Amran, Ahmed G. Rady","doi":"10.18805/ijar.bf-1750","DOIUrl":null,"url":null,"abstract":"Background: The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening. Methods: A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks. Result: Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P less than 0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.\n","PeriodicalId":13410,"journal":{"name":"Indian Journal of Animal Research","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigating the Impact of Launaea angustifolia Extract on the Reproduction Function of Female Rats\",\"authors\":\"A. Ammari, A. Alhimaidi, R. Amran, Ahmed G. Rady\",\"doi\":\"10.18805/ijar.bf-1750\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening. Methods: A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks. Result: Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P less than 0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.\\n\",\"PeriodicalId\":13410,\"journal\":{\"name\":\"Indian Journal of Animal Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-04-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Animal Research\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.18805/ijar.bf-1750\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Animal Research","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.18805/ijar.bf-1750","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
Investigating the Impact of Launaea angustifolia Extract on the Reproduction Function of Female Rats
Background: The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening. Methods: A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks. Result: Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P less than 0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.
期刊介绍:
The IJAR, the flagship print journal of ARCC, it is a monthly journal published without any break since 1966. The overall aim of the journal is to promote the professional development of its readers, researchers and scientists around the world. Indian Journal of Animal Research is peer-reviewed journal and has gained recognition for its high standard in the academic world. It anatomy, nutrition, production, management, veterinary, fisheries, zoology etc. The objective of the journal is to provide a forum to the scientific community to publish their research findings and also to open new vistas for further research. The journal is being covered under international indexing and abstracting services.