限时进食(中午 12 点至晚上 8 点进食)比限制热量摄入对减肥和血糖控制更有效吗?

Alyson Hill
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引用次数: 0

摘要

这项为期 6 个月的随机临床试验评估了限时进食(TRE)与每日热量限制(CR)相比,对 2 型糖尿病(T2DM)和肥胖症患者的有效性和安全性。这项研究有 75 名参与者参加,测量了体重、血红蛋白 A1c (HbA1c) 水平和代谢风险因素的变化。参与者被随机分为 3 个不同的组别:(1)TRE 组(从中午 12 点到晚上 8 点进食,不计算卡路里);(2)CR 组(每天限制 25% 的能量);(3)对照组。结果表明,与对照组相比,TRE 组的体重减轻和 HbA1c 水平降低具有显著的统计学意义。然而,CR 组的体重没有明显减轻。没有严重不良事件的报告。这项研究表明,TRE 可以作为一种有效的策略,帮助患有 T2D 的患者减轻体重和控制血糖,但还需要进行样本量更大、随访时间更长的进一步研究,以证实这些研究结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is Time-Restricted Eating (Eating 12–8pm) More Effective for Weight Loss and Glycaemic Control than Calorie Restriction?
This 6-month randomized clinical trial evaluated the effectiveness and safety of time-restricted eating (TRE) compared to daily calorie restriction (CR) in individuals with type 2 diabetes mellitus (T2DM) and obesity. The study involved 75 participants and measured changes in body weight, haemoglobin A1c (HbA1c) levels, and metabolic risk factors. Participants were randomized to 1 of 3 different groups: (1) TRE (eating from 12 to 8pm, without calorie counting), (2) CR (25% energy restriction daily), (3) control. Results showed that the TRE group experienced statistically significant weight loss and reductions in HbA1c levels compared to the control group. However, the CR group did not show significant weight loss. No serious adverse events were reported. The study suggests that TRE could be an effective strategy for weight loss and glycaemic control in individuals with T2D, but further research with larger sample sizes and longer follow-up periods is needed to confirm these findings.
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