目前对 ALK 阳性无细胞大细胞淋巴瘤病因和发病机制的看法

Q4 Medicine

Pediatric Hematology/Oncology and Immunopathology Pub Date : 2024-04-08 DOI:10.24287/1726-1708-2024-23-1-180-191

D. Abramov, A. Fedorova, E. Volchkov, N. Myakova, D. M. Konovalov

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引用次数: 0

摘要

ALK阳性无性大细胞淋巴瘤是一种成熟的T细胞淋巴瘤，其特征是涉及ALK受体酪氨酸激酶编码基因的易位。据了解，这种疾病几乎只影响儿童和年轻人。目前，对ALK阳性无性大细胞淋巴瘤的生物学研究相当深入，最近的研究主要集中在这种肿瘤的组织发生上。在这篇综述中，我们分析了有关这种疾病的病因学和发病机制的现有世界文献数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Current views on the etiology and pathogenesis of ALK-positive anaplastic large cell lymphoma

ALK-positive anaplastic large cell lymphoma is a mature T-cell lymphoma characterized by translocations that involve the ALK receptor tyrosine kinase coding gene. This illness is known to almost exclusively affect children and young adults. The biology of ALK-positive anaplastic large cell lymphoma is fairly well researched today, with recent studies focusing on the histogenesis of this neoplasm. In this review, we analyze the existing world literature data on the etiology and pathogenesis of this disease.

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来源期刊

Pediatric Hematology/Oncology and Immunopathology Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.40

自引率

0.00%

发文量