虚弱前兆的严重程度与 Ninjin'yoeito(NYT)对虚弱前兆的适应程度之间的关系

Haruka Amitani, Hajime Suzuki, Hironori Kobayashi, Masaru Murayama, N. Uto, Eishi Kuroda, Yoshiki Kobayashi, Momoko Kawabe, Marie Amitani, Akio Inui, Yoshinori Marunaka
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引用次数: 0

摘要

随着全球人口预期寿命延长的趋势,人们越来越重视不仅要延年益寿,还要在年老时保持健康和幸福。本研究探讨了宁神悦瞳(NYT)在身体虚弱早期阶段的功效,这是预防性干预的关键时期。考虑到有关早期虚弱与 NYT 之间关系的知识空白,我们利用工作场所健康检查的数据来研究虚弱前期严重程度与 NYT 适应性之间的关系。我们的研究目的是加强对使用 NYT 进行早期治疗的理解,以防止体弱的恶化。在 2021 年 11 月至 2023 年 3 月期间接受工作场所健康检查并同意本研究的京都产业健康协会的 314 名员工被纳入分析范围。研究人员获得了有关性别、年龄、体重指数(BMI)、纽约时报特定症状评估、日语版《一般健康问卷-12》(GHQ-12)和《Kihon检查表》(KCL)的信息。相关性分析显示,适用的纽约时报适应症数量与 GHQ-12 评分之间存在很强的正相关性(r = 0.5992,p < 0.0001)。同样,在适用的 NYT 适应症数量与 KCL 评分之间也观察到中度正相关(r = 0.5030,p < 0.0001)。在多变量分析中,GHQ-12(β = 0.49,SE = 0.06,t = 7.66,95% CI:0.36 至 0.62,p = 0.000)和 KCL(β = 0.54,SE = 0.12,t = 4.29,95% CI:0.29 至 0.79,p = 0.000)均与适用 NYT 适应症数量的差异呈显著正相关,表明这些指标的得分越高,适应症数量越多。NYT不仅有可能作为一种治疗虚弱的干预措施,也有可能作为一种预防措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between the severity of pre-frailty and the degree of adaptation of Ninjin’yoeito (NYT) on pre-frailty
With the global trend towards longer life expectancies, there’s an increasing emphasis on not just living longer, but also maintaining health and wellbeing into older age. This study explores the efficacy of Ninjin’yoeito (NYT) in the early stages of frailty, a critical period for preventive interventions. Taking account of the knowledge gap regarding the association between early frailty and NYT, we use data from workplace health checkups to examine the relationship between pre-frailty severity and NYT adaption. The objective of our research is to enhance the comprehension of early treatments using NYT to prevent the progression of frailty. A total of 314 employees of the Kyoto Industrial Health Association who received workplace health checkups between November 2021 and March 2023 and consented to this study were included in the analysis. Information on gender, age, body mass index (BMI), NYT-specific symptoms assessment, the Japanese version of the General Health Questionnaire-12 (GHQ-12), and the Kihon Checklist (KCL) were obtained. The correlation analysis revealed that there was a strong positive correlation between the number of applicable NYT indications and the GHQ-12 score (r = 0.5992, p < 0.0001). Similarly, a moderate positive correlation was observed between the number of applicable NYT indications and the KCL score (r = 0.5030, p < 0.0001). In the multivariate analysis, both GHQ-12 (β = 0.49, SE = 0.06, t = 7.66, 95% CI: 0.36 to 0.62, p = 0.000) and KCL (β = 0.54, SE = 0.12, t = 4.29, 95% CI: 0.29 to 0.79, p = 0.000) showed significant positive associations with the variance in the number of applicable NYT indications, indicating that higher scores on these measures were related to a greater number of indications. NYT has the potential to be utilized not only as a therapeutic intervention for frailty, but also as a preventive measure.
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