The use of mesenchymal stem cells in tendon regeneration in rats.

Mesenchymal stem cells are of great interest due to their regenerative potential and capacity to transdifferentiate into various cell lineages. The present study executed a narrative review of the literature on the influence of mesenchymal stem cells on the regeneration of tendon injuries. To acomplish this, a search was carried out in the Pubmed and Scielo databases using descriptors such as: Mesenchymal stem cell regeneration and application tendon rat; Embryonic Stem Cell-Derived Mesenchymal Stem Cells for Tendon Tissue rat. Only research articles carried out on rats between 2011 and 2023 were included. 935 articles were found in the Pubmed database, and 43 articles were included based on the criteria of categorization, analysis of titles and abstracts. The articles showed benefits in relation to the use of stem cells in rat tendon injuries, but some studies showed that this repair was not 100% guaranteed to the state of the tendon originally, but associated with growth factors obtained a better induction of tenogenesis.