接受血液透析的糖尿病患者高尿酸血症与高血压之间的关系

Anahita Arian, Hamid Salehiniya, Tina Erfani, V. Raeesi
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摘要

背景:糖尿病是一种常见的慢性疾病,被认为是其他慢性疾病的风险因素。多项研究指出了尿酸与 2 型糖尿病之间的关系。研究目的本研究旨在调查接受血液透析的糖尿病患者高尿酸血症与高血压之间的关系。研究方法本研究对 2022 年转诊至比尔詹德特殊疾病综合治疗中心的透析患者进行了描述性分析横断面研究。数据通过核对表收集,其中包括年龄、性别、血液透析持续时间、糖尿病持续时间、基础疾病史、血压和血清尿酸水平等信息。数据使用 SPSS 26 软件进行分析,并进行卡方检验、费雪精确检验和曼-惠特尼检验,显著性水平为 0.05。结果61名患者(85.9%)患有高血压。尿酸平均水平为 5.9 ± 1.12,11 例(15.5%)患者出现高尿酸血症。虽然高血压患者的高尿酸血症发生率较高 [10 (16.4%) vs. 1 (10%)],但未观察到高尿酸血症与高血压之间存在显著关系 (P = 0.605)。此外,平均尿酸水平与人口统计学因素(年龄、性别、透析时间和平均血糖)之间也无明显关系(P > 0.05)。结论本研究结果显示,高血压透析患者的高尿酸血症发生率高于非高血压患者。然而,由于这种关系并不显著,因此有必要进行样本量更大的研究,以真正了解血液透析糖尿病患者高尿酸血症与高血压之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship Between Hyperuricemia and Hypertension in Diabetic Patients Undergoing Hemodialysis
Background: Diabetes is a prevalent chronic disease and is considered a risk factor for other chronic diseases. Various studies have pointed out the relationship between uric acid and type 2 diabetes. Objectives: This study aimed to investigate the relationship between hyperuricemia and hypertension in diabetic patients undergoing hemodialysis. Methods: The descriptive-analytical cross-sectional study was conducted on dialysis patients referred to the Comprehensive Center for the Treatment of Special Diseases in Birjand in 2022. Data were collected through a checklist, which included information such as age, sex, duration of hemodialysis, duration of diabetes, history of underlying diseases, blood pressure, and serum uric acid level. The data were analyzed using SPSS 26 software and chi-square, Fisher's exact, Mann-Whitney tests with a significance level of 0.05. Results: Hypertension was present in 61 (85.9%) of patients. The average uric acid level was 5.9 ± 1.12, and hyperuricemia was observed in 11 (15.5%) of patients. Although the rate of hyperuricemia was higher in patients with high blood pressure [10 (16.4%) vs. 1 (10%)], no significant relationship between hyperuricemia and high blood pressure was observed (P = 0.605). Additionally, no significant relationship was observed between the average uric acid level and demographic factors (age, sex, duration of dialysis, and average blood sugar) (P > 0.05). Conclusions: According to the present study's results, the rate of hyperuricemia in dialysis patients with high blood pressure is higher than in patients without high blood pressure. However, due to the non-significance of this relationship, there is a need to conduct studies with a larger sample size to truly understand its relationship with high blood pressure in diabetic patients undergoing hemodialysis.
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