塞内加尔达喀尔 Aristide LeDantec 医院皮肤科的免疫过敏性皮肤病:流行病学、临床和病因模式

C. Ndiaye, B. Diatta, Maodo Ndiaye, K. Diop, S. Niang
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摘要

背景:近十年来,非洲地区的免疫过敏性皮肤病发病率不断上升。在塞内加尔,免疫过敏性皮肤病是皮肤病的第一主诉病症。我们的目的是描述其流行病学、临床和病因模式。研究方法:我们在达喀尔阿里斯蒂德-勒当泰克医院皮肤科开展了一项为期一年(2020 年 4 月至 2021 年 4 月)的前瞻性描述性研究。我们招募了住院病人和门诊病人。结果在接诊的 5633 名患者中,共汇总了 149 个病例,发病率为 2.6%。平均年龄为 31.42 岁。特应性皮炎是第一种免疫过敏性皮肤病,占 66.4%。其次是毒皮肤病(16.1%)、接触性皮炎(12.75%)和荨麻疹(4.69%)。对 14.1%的特应性皮炎患者进行了呼吸道点刺试验,结果有 57.1%的患者呈阳性。在荨麻疹和/或血管性水肿患者中,57.14%的病例的主要诱发因素是使用药物。在我们的研究中,抗生素是我们的患者中第一种与药物有关的毒血症,占 41.7%。其次是草药治疗,占 29.2%,扑热息痛占 16.7%。结论迄今为止,免疫过敏性皮肤病在我们的机构中占第一主诉病症,并且以特应性皮炎为主。自动药物治疗和草药治疗是公共卫生问题。它们通常会导致最严重的毒皮炎,因此可能会造成重大威胁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immuno-allergic dermatoses in the Dermatology Department of Aristide LeDantec Hospital, Dakar, Senegal: Epidemiological, clinical, and etiological patterns
Background: Immuno-allergic dermatoses have been highly increasing for a decade in African settings. They are the first chief complaint of dermatological conditions in Senegal. Our objective was to describe their epidemiological, clinical, and etiological patterns. Methodology: We conducted a looking-forward descriptive study for 1 year ranging from April 2020 to April 2021 in the Dermatology Department of Aristide LeDantec Hospital in Dakar. We recruited both inpatients and outpatients. Results: Among 5633 patients received for consultation, 149 cases were pooled accounting for a prevalence of 2,6%. The mean age was 31,42 years old. Atopic dermatosis was the first immuno-allergic dermatosis representing 66,4%. They were followed by toxidermia in 16,1% of cases, contact dermatitis in 12,75% of cases, and urticaria in 4,69%. For patients with atopic dermatosis, a respiratory prick test was carried out in 14,1% of patients with a positivity in 57,1% of cases. Of the patients with urticaria and/or angioedema, the main triggering factor was drug use in 57,14% of cases. In our study, antibiotics were the first drug-related toxidermia in our patients accounting for 41,7% of cases. They were followed by herbal therapy in 29,2% of cases and paracetamol in 16,7% of cases. Conclusion: To date, immuno-allergic dermatoses constitute the first chief complaint in our structure and are by far dominated by atopic dermatitis. Automedication and herbal therapy are public health concerns. By causing toxidermia, often in their most serious patterns, they can have a vital prone-threat involvement.
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