实验室标准在腰椎经关节固定术后并发症风险评估中的应用

O. Barkov, V. Tuliakov, Valerija Aplevich
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Comparison was made with a control group (20 practically healthy people). Results. Patients have a significant increase in serum ALT activity by 42.29 and AST by 63.55 %, by 38.37 % of the level of CS content, by 37.21 % of total glycoproteins compared to those in the control group. In patients with soft tissue inflammation around the serum instrument zone, the content of LDLP was recorded by 29.27 %, by 23.53 % of the UA, by 12.34 % of TP results higher by 32.01 % ALT activity and 83 %, 49 % AST, 54.96 % AlP activity, 31.40 % — AlP/AcP, 60.47 % — concentration of CS, 95.57 % — total glycoproteins than in persons in the control group. In the serum of patients with the development of instability of metal structures, 28.55 % was observed by activity of the ALT, AlP — by 38.47 %, AcP — by 48.84 %, less by 58.35 % of AlP/AcP, the CHOL content of 13 88 %, higher by 25.43 % of the LDLP content than such persons in the control group. 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摘要

目的研究通过经椎间孔固定手术治疗腰椎退行性疾病术后并发症发生的特殊性及其与术前实验室参数变化的关系。方法。对 35 名接受椎间盘切除术和经椎弓根固定术的腰椎退行性疾病患者的生化检查数据进行回顾性分析。四组患者出现术后并发症:10名患者--金属结构周围的织物发炎,5名患者--金属结构不稳定。20 名无特定并发症患者的检查结果作为对比组。与对照组(20 名身体健康者)进行比较。检查结果与对照组相比,患者的血清谷丙转氨酶(ALT)活性明显升高了 42.29%,谷草转氨酶(AST)升高了 63.55%,CS 含量升高了 38.37%,糖蛋白总量升高了 37.21%。与对照组相比,血清仪器区周围软组织炎症患者的 LDLP 含量增加了 29.27%,UA 增加了 23.53%,TP 增加了 12.34%,ALT 活性增加了 32.01%,AST 增加了 83%,AST 增加了 49%,AlP 活性增加了 54.96%,AlP/AcP 增加了 31.40%,CS 浓度增加了 60.47%,糖蛋白总量增加了 95.57%。在出现金属结构不稳定的患者血清中,ALT 活性降低了 28.55%,AlP 降低了 38.47%,AcP 降低了 48.84%,AlP/AcP 降低了 58.35%,CHOL 含量降低了 13.88%,LDLP 含量比对照组患者高出 25.43%。P 含量比对照组低 31.51 %,Ca/P 比值比对照组高 38.95 %,CS 含量比对照组高 83.72 %,糖蛋白总量比对照组高 48.83 %。结论对脊柱退行性疾病患者术前的临床和实验室检查结果进行比较分析,结果显示他们术前的实验室参数与类似手术后无并发症的患者术前参数存在偏差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE USE OF LABORATORY CRITERIA IN THE RISK ASSESSMENT OF POSTOPERATIVE COMPLICATIONS AFTER TRANSPEDICULAR FIXATION OF THE LUMBAR SPINE
Objective. To investigate the peculiarities of the development of postoperative complications after surgical treatment of degenerative diseases of the lumbar spine with transpedicular fixation of the vertebrae and their relationship with changes in preoperative laboratory parameters. Methods. A retrospective analysis of the biochemical examination data of 35 patients with degenerative diseases of the lumbar spine who underwent discectomy with transpedicular fixation was performed. In four groups of patients with postoperative complications: 10 patients — inflammation of the what fabrics around metal structures and 5 patients — instability of the metal structure. The results of the examination of 20 people without specified complications served as a comparison group. Comparison was made with a control group (20 practically healthy people). Results. Patients have a significant increase in serum ALT activity by 42.29 and AST by 63.55 %, by 38.37 % of the level of CS content, by 37.21 % of total glycoproteins compared to those in the control group. In patients with soft tissue inflammation around the serum instrument zone, the content of LDLP was recorded by 29.27 %, by 23.53 % of the UA, by 12.34 % of TP results higher by 32.01 % ALT activity and 83 %, 49 % AST, 54.96 % AlP activity, 31.40 % — AlP/AcP, 60.47 % — concentration of CS, 95.57 % — total glycoproteins than in persons in the control group. In the serum of patients with the development of instability of metal structures, 28.55 % was observed by activity of the ALT, AlP — by 38.47 %, AcP — by 48.84 %, less by 58.35 % of AlP/AcP, the CHOL content of 13 88 %, higher by 25.43 % of the LDLP content than such persons in the control group. Content of the P was lower by 31.51 % and the Ca/P ratio was higher by 38.95 %, the content of CS by 83.72 %, total glycoproteins — by 48.83 %. Conclusions. Comparative analysis of the results of preoperative clinical and laboratory examination of patients with degenerative spinal diseases with transpedicular fixation which is reflected in the deviations of their preoperative laboratory parameters from such persons with uncomplicated course of the postoperative period after similar surgery.
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