肝性脑病中的抗惊厥药

Sona Jose, Amal Roy, N. M. Amala, C. S. Vidhya, Lincy George
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摘要

肝性脑病(HE)是一种复杂的神经系统综合征,是肝功能异常的并发症。传统上,肝性脑病治疗的主要重点是氨解毒,但最近的研究揭示了抗惊厥药物在改善肝性脑病相关认知障碍和预防癫痫发作方面的潜在作用。本综述的主要目的是全面分析抗惊厥药物在肝性脑病中的应用,研究其作用机制、疗效和安全性。关键词肝性脑病 抗惊厥药 认知障碍
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anticonvulsants in Hepatic Encephalopathy
Hepatic encephalopathy (HE) is a complex neurological syndrome that arises as a complication of liver dysfunction. The primary focus in HE management has traditionally been on ammonia detoxification, but recent research has paved light on the potential role of anticonvulsant medications in improving the cognitive impairment and preventing seizures associated with HE. This review mainly aims to provide a comprehensive analysis of the use of anticonvulsants in hepatic encephalopathy, by taking a looking at their mechanisms of action, efficacy, and safety profiles. Keywords: Hepatic encephalopathy, Anticonvulsants, Cognitive impairment
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