氧杂蒽酮衍生物：多用途药理学全景图

Q2 Pharmacology, Toxicology and Pharmaceutics

Current Bioactive Compounds Pub Date : 2024-04-18 DOI:10.2174/0115734072278162240406123303

Anuradha Mehra, Rekha Sangwan, Emmanuel Owusu

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引用次数: 0

摘要

氧杂蒽酮是一类存在于各种植物资源中的天然化合物。多年来的研究表明，氧杂蒽酮可治疗和控制多种疾病，包括癌症、炎症和微生物感染。氧杂蒽酮通过各种机制发挥治疗作用，如抗炎、抗氧化和抗增殖活性。研究还发现，氧杂蒽酮可通过调节多种信号通路诱导细胞凋亡、抑制细胞增殖和阻滞细胞周期。这篇综述旨在全面概述氧杂蒽酮的治疗本质，以及其作为天然疗法管理和治疗各种疾病的潜力。

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Xanthone Derivatives: A Pharmacological Panorama of Versatility

Xanthones are a class of naturally occurring compounds found in various plant sources. Over the years, studies have revealed therapeutic impending xanthones in treating and managing several ailments, including cancer, inflammation, and microbial infections. Xanthones exert their therapeutic effects through various mechanisms, such as anti-inflammatory, antioxidant, and anti-proliferative activities. It has also been found that xanthones induce apoptosis, inhibit cell proliferation, and arrest cell cycles by modulating several signaling pathways. This review objective is to deliver an inclusive overview of the therapeutic essence of xanthones and their potential use as a natural remedy for managing and treating various diseases.

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来源期刊

Current Bioactive Compounds Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

1.90

自引率

0.00%

发文量

112

期刊介绍： The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.