辣木（Moringa oleifera）叶面乙醇提取物对阿洛糖诱导的雄性猕猴血糖降低的影响

Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Pub Date : 2024-04-20 DOI:10.32539/jkk.v11i2.416

Ditya Ananda Safira, Susianti, Dyah Wulan Sumekar, Rengganis Wardani, J. Suwandi, Ditya Ananda, Safira, Kata Kunci, Tepung Daun, Kelor Moringa

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引用次数: 0

摘要

本研究旨在确定给予辣木叶粉（Moringa oleifera）乙醇提取物对降低阿洛糖诱导的 Wistar Rattus norvegicus 雄性大鼠血糖水平的影响。该研究采用了真正的实验设计和随机的前后对照组方法。使用的样本包括 35 只雄性 Wistar 白鼠。采用简单随机抽样技术收集数据。所有治疗组的配对 t 检验结果均为 p<0.05，这意味着高血糖大鼠在治疗前后的空腹血糖水平存在差异。单因素方差分析的结果为 p<0.001，这意味着所有治疗组治疗前后的空腹血糖平均值差异显著。LSD 事后检验结果显示，P1 和 P2 治疗前后的空腹血糖平均值与所有治疗组相比均有显著差异（P<0.001）。Probit 分析测试得出 ED50=1447,84 mg/kgBB。

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EFFECT OF MORINGA (Moringa oleifera) LEAF FLOUR ETHANOL EXTRACT ON REDUCTION OF BLOOD GLUCOSE IN MALE WISTAR STRAIN RATS INDUCED BY ALLOXAN

This study is to determine the effect of giving ethanol extract of moringa leaf flour (Moringa oleifera) on reducing blood glucose levels of alloxan-induced Wistar Rattus norvegicus male rats. Using a true experimental design with a randomized pre and post control group approach. The sample used consisted of 35 male Wistar white rats. Data collection using simple random sampling technique. Paired t test gives the results of p<0.05 in all treatment groups, meaning that there are differences in fasting blood glucose levels of hyperglycemic rats before and after treatment. One way ANOVA test gave the result of p<0.001, meaning that all treatment groups showed a significant difference in the mean difference in fasting blood glucose levels before and after treatment. LSD post hoc test results showed a significant mean difference in fasting blood glucose levels before and after treatment of P1 and P2 with all treatment groups (p<0.001). Probit analysis test obtained ED50=1447,84 mg/kgBB.

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Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya

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