慢性肝病门静脉高压非侵入性评估与侵入性评估的比较

R. Gaspar, Guilherme Macedo
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引用次数: 0

摘要

背景:肝硬化是全球发病和死亡的主要原因之一,也是消化系统疾病死亡的第二大原因。门静脉高压是导致腹水和静脉曲张出血等肝硬化相关并发症的主要原因。门静脉高压的定义是肝静脉压力梯度大于 5 毫米汞柱,但当压力梯度大于 10 毫米汞柱时,门静脉高压具有临床意义并与临床并发症相关。摘要:因此,检测慢性晚期肝病或代偿期肝硬化患者的临床意义门静脉高压症(CSPH)对指导这些患者的治疗至关重要。关键信息:本研究旨在修订用于评估慢性肝病患者门静脉高压和 CSPH 风险分层的无创和有创工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-Invasive versus Invasive Assessment of Portal Hypertension in Chronic Liver Disease
Background: Cirrhosis is one of the major causes of morbidity and mortality worldwide and the second leading cause of digestive disease mortality. Portal hypertension is the main driver of cirrhosis-related complications such as ascites and variceal bleeding. Portal hypertension is defined as a hepatic venous pressure gradient >5 mm Hg, although it is clinically significant and associated with clinical complications when >10 mm Hg. Summary: Therefore, detection of clinically significant portal hypertension (CSPH) in chronic advanced liver disease or compensated cirrhosis is of paramount importance to guide the management of these patients. Key Messages: This study aimed at revising the non-invasive and invasive tools for assessment of portal hypertension and risk stratification for CSPH in patients with chronic liver disease.
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