ReDIP,意大利先天性血小板功能障碍诊断网络

Marco Cattaneo, Claudia Ghali, M. Scavone
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引用次数: 0

摘要

先天性血小板功能障碍(cPFD)与不同严重程度的皮肤粘膜出血风险增加有关;可根据具有共同特征的血小板成分异常进行分类:i) 黏附蛋白的血小板受体;ii) 可溶性激动剂的血小板受体;iii) 血小板颗粒;iv) 信号转导途径;v) 促凝血磷脂;特征不明显的先天性血小板功能障碍被归入第六类杂项异常[...]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ReDIP, the Italian network for the diagnosis of congenital platelet function disorders
Congenital platelet function disorders (cPFD) are associated with an increased risk of mucocutaneous bleeding of various levels of severity; they may be classified based on abnormalities of platelet components that share common characteristics: i) platelet receptors for adhesive proteins; ii) platelet receptors for soluble agonists; iii) platelet granules; iv) signal transduction pathways; v) procoagulant phospholipids; less well characterized PFD aregrouped in a sixth category of miscellaneous abnormalities [...].
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