Wajeeha Aiman, Muhammad Ashar Ali, Navjot Grewal, Andreas A. Savopoulos, G. Guron
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引用次数: 0
摘要
由于获得性蛋白 C 和 S 缺乏、抗磷脂抗体综合征以及促炎细胞因子水平升高等因素,人类免疫缺陷病毒(HIV)感染患者发生静脉血栓栓塞(VTE)的可能性增加。本病例报告强调了一名接受治疗剂量依诺肝素的 HIV 感染者发生深静脉血栓的异常罕见情况。这强调了即使接受了预防性或治疗性抗凝剂治疗,也需要谨慎考虑 HIV 感染者发生 VTE 的风险。建议开展进一步研究,将 HIV 作为预防性抗凝治疗的潜在风险因素进行调查。
A Case of Deep Venous Thrombosis in an HIV-Infected Patient despite Therapeutic Anticoagulation
Patients with human immunodeficiency virus (HIV) infection have an increased likelihood of venous thromboembolism (VTE) owing to factors such as acquired protein C and S deficiency, antiphospholipid antibody syndrome, and heightened levels of pro-inflammatory cytokines. This case report highlights an exceptionally uncommon occurrence of deep venous thrombosis in an HIV-infected patient receiving a therapeutic dose of enoxaparin. This underscores the need for cautious consideration of the risk of VTE in HIV-infected individuals, even with preventive or therapeutic anticoagulant treatment. Further research is recommended to investigate HIV as a potential risk factor of prophylactic anticoagulation.