股骨近端骨折术前死亡率预测因素

S. S. Rodionova, Habiballah Zaid A. Asi, A. V. Krivova, Elmira M. Murtazina
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引用次数: 0

摘要

背景:年龄和合并症被认为是股骨近端骨折患者术前死亡率的独立预测因素,但它们的作用仍有待商榷。目的:评估年龄和查尔森合并症指数(Charlson Comorbidity Index,CCI)对股骨近端骨折老年人生存的预后意义。材料与方法:这项回顾性前瞻性研究纳入了特维尔市、托尔若克市、热夫市、维什尼沃罗切克市和卡申市 50 岁以上老年人在 2019 年 1 月 1 日至 2019 年 12 月 31 日期间发生的所有股骨近端骨折病例。ICD-10 编码S72.0、S72.1 和 S72.2。每位患者的 CCI 均通过在线计算器以及从患者和门诊病历中获取的临床数据计算得出。统计分析。采用卡普兰-梅耶曲线和平均每天每千人死亡人数估算生存率。随访间隔以天为单位,从受伤到死亡或最后一次接触患者。观察期最短为 876 天,最长为 1492 天。结果:无论是接受手术的患者还是未接受手术的患者,其存活率都从低年龄组向高年龄组下降。年龄≥85岁的患者风险最大(中位生存期:257天;95% CI:36.6-478.3)。CCI与存活率明显相关:CCI为3时的死亡风险是CCI为2-3时的3-6倍,具体取决于随访间隔。CCI比年龄更能反映健康状况:在同一年龄组中,有不同CCI的患者。结论:同时使用年龄和 CCI 作为死亡率的预测指标和健康状况的更准确指标,将有助于规划术前和术后额外医疗和社会资源的使用,从而提高存活率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperative predictors of mortality in fractures of the proximal femur
BACKGROUND: Age and comorbidities are considered independent preoperative predictors of mortality in proximal femoral fractures; however, their contribution remains debatable. AIM: To assess the prognostic significance of age and Charlson Comorbidity Index (CCI) of the survival of older people with proximal femoral fractures. MATERIALS AND METHODS: This retrospective prospective study included all cases of proximal femoral fractures that occurred between January 1, 2019, and December 31, 2019, in individuals over 50 years of age from the cities of Tver, Torzhok, Rzhev, VyshnyVolochek, and Kashin. ICD-10 codes: S72.0, S72.1, and S72.2. The CCI of each patient was calculated using an online calculator and clinical data obtained from patient and outpatient records. Statistical analysis. Survival was estimated using Kaplan–Meier curves and the average number of deaths per day per 1000 people. The follow-up interval was obtained in days from the time of injury to the event of death or last contact with the patient. The minimum observation period was 876 days, and the maximum was 1492 days. RESULTS: The survival rate of patients decreased from younger to older age groups, both among those operated on and those who were not. Patients aged ≥85 years were at greatest risk (median survival: 257 days; 95% CI: 36.6–478.3). CCI was significantly associated with survival: the risk of death with CCI 3 was 3–6 times higher than that with CCI 2–3, depending on the follow-up interval. CCI reflected health status more than age: within the same age group, there were patients with different CCIs. CONCLUSION: Using age and CCI simultaneously as predictors of mortality and more accurate indicators of health status will enable the planning of the utilization of additional medical and social resources in the preoperative and postoperative periods, thereby increasing survival.
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