乳腺癌治疗方案和周期计数的机器学习分析:摩洛哥穆罕默德六世医院案例研究

Houda AIT BRAHIM, Salah EL-HADAJ, Abdelmoutalib METRANE
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引用次数: 0

摘要

本文介绍了一项基于机器学习算法预测乳腺癌患者治疗方案和相应治疗周期的新研究。所使用的数据是在摩洛哥穆罕默德六世医院收集的,其中包含两个目标(治疗方案和治疗周期)的患者信息:第一个模型基于梯度提升分类器算法,成功地对患者治疗方案进行了分类,所有类别的总体准确率为 64%,而医院广泛采用的模式类别的准确率高达 94%,令人印象深刻。第二个模型基于随机森林回归算法,在训练过程中整合了第一个模型的结果,以 0.050 的均方根误差 (RMSE) 和 0.020 的平均绝对百分比误差 (MAPE) 预测了患者的治疗周期。最后,这项研究可以帮助医生快速决定每位患者所需的治疗方法,还可以根据预测的患者治疗周期了解医院库存中应该有哪些分子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Machine learning analysis of breast cancer treatment protocols and cycle counts: A case study at Mohammed vi hospital, Morocco

This paper presents a new study of predicting patients' breast cancer treatment protocol and the corresponding treatment cycle based on machine learning algorithms. The data used were collected at Mohammed VI Hospital in Morocco, and it contains patient information with two targets (protocol and treatment cycle).

After preparing the data and testing several machine learning algorithms, two models were developed: The first one, based on Gradient Boosting Classifier algorithm, successfully classified patient treatment protocols with an overall accuracy of 64 % across all categories and an impressive 94 % accuracy for the mode category, widely adopted in the hospital. The second model, based on Random Forest Regressor algorithm, which integrates the results of the first model during the training, predicted the treatment cycle of patients with a Root Mean Square Error (RMSE) score of 0.050 and a Mean Absolute Percentage Error (MAPE) score of 0.020. Furthermore, feature importance analysis was performed to highlight the importance of variables, and show the positive influence of some variables on the models.

Finally, this study can help doctors quickly make decisions about the treatment needed for each patient and also gives an idea of which molecules should exist in the hospital stock based on the patient's treatment cycle predicted.

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