Ben Jacob Novak, Pete Gober, Robyn Bortner, Della Garelle, Mary Wright, Justin Novak, Marlys L Houck, Oliver A Ryder, Dennis Milutinovich, Jill Benavidez, Kerry Ryan, Shawn Walker, Sanaz Sadeghieh Arenivas, Lauren Aston, Blake Russell, Paul Marinari, Adrienne Crosier, Kelly Helmick, Mary R Gibson, Daniel P Carlson, Bradley J Swanson, Samantha M Wisely, Zoe S White, Colleen Lynch, Ryan Phelan
{"title":"克隆首只濒危黑脚雪貂以拯救基因","authors":"Ben Jacob Novak, Pete Gober, Robyn Bortner, Della Garelle, Mary Wright, Justin Novak, Marlys L Houck, Oliver A Ryder, Dennis Milutinovich, Jill Benavidez, Kerry Ryan, Shawn Walker, Sanaz Sadeghieh Arenivas, Lauren Aston, Blake Russell, Paul Marinari, Adrienne Crosier, Kelly Helmick, Mary R Gibson, Daniel P Carlson, Bradley J Swanson, Samantha M Wisely, Zoe S White, Colleen Lynch, Ryan Phelan","doi":"10.1101/2024.04.17.589896","DOIUrl":null,"url":null,"abstract":"An endangered black-footed ferret female that died in 1988 with no living descendants in the current population was successfully cloned from cryopreserved cells using cross-species somatic cell nuclear transfer, producing three healthy kits. Incorporating progeny from these clones would provide an 8th founder to the breeding program and increase genetic variation to the species' limited gene-pool. This marks the first time a native U.S. endangered species has been cloned.","PeriodicalId":501575,"journal":{"name":"bioRxiv - Zoology","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"First endangered black-footed ferrets, Mustela nigripes, cloned for genetic rescue\",\"authors\":\"Ben Jacob Novak, Pete Gober, Robyn Bortner, Della Garelle, Mary Wright, Justin Novak, Marlys L Houck, Oliver A Ryder, Dennis Milutinovich, Jill Benavidez, Kerry Ryan, Shawn Walker, Sanaz Sadeghieh Arenivas, Lauren Aston, Blake Russell, Paul Marinari, Adrienne Crosier, Kelly Helmick, Mary R Gibson, Daniel P Carlson, Bradley J Swanson, Samantha M Wisely, Zoe S White, Colleen Lynch, Ryan Phelan\",\"doi\":\"10.1101/2024.04.17.589896\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An endangered black-footed ferret female that died in 1988 with no living descendants in the current population was successfully cloned from cryopreserved cells using cross-species somatic cell nuclear transfer, producing three healthy kits. Incorporating progeny from these clones would provide an 8th founder to the breeding program and increase genetic variation to the species' limited gene-pool. This marks the first time a native U.S. endangered species has been cloned.\",\"PeriodicalId\":501575,\"journal\":{\"name\":\"bioRxiv - Zoology\",\"volume\":\"22 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"bioRxiv - Zoology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.04.17.589896\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"bioRxiv - Zoology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.17.589896","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
First endangered black-footed ferrets, Mustela nigripes, cloned for genetic rescue
An endangered black-footed ferret female that died in 1988 with no living descendants in the current population was successfully cloned from cryopreserved cells using cross-species somatic cell nuclear transfer, producing three healthy kits. Incorporating progeny from these clones would provide an 8th founder to the breeding program and increase genetic variation to the species' limited gene-pool. This marks the first time a native U.S. endangered species has been cloned.
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