赖氨酸与盐敏感性高血压

IF 2.2 3区医学 Q3 PERIPHERAL VASCULAR DISEASE

Current Opinion in Nephrology and Hypertension Pub Date : 2024-04-22 DOI:10.1097/mnh.0000000000000994

Lashodya V Dissanayake, Oleg Palygin, Alexander Staruschenko

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引用次数: 0

摘要

人们对盐敏感性高血压及其相关的肾损伤进行了广泛的研究，但却缺乏适当的治疗策略。通过改变代谢组来影响肾脏和心血管疾病的研究正在兴起。在此，我们讨论了赖氨酸（一种必需氨基酸）对 SS 高血压进展的保护作用及其背后的潜在机制。

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Lysine and salt-sensitive hypertension.

Salt-sensitive (SS) hypertension and its associated kidney damage have been extensively studied, yet proper therapeutic strategies are lacking. The interest in altering the metabolome to affect renal and cardiovascular disease has been emerging. Here, we discuss the effect and potential mechanism behind the protective effect of lysine, an essential amino acid, on the progression of SS hypertension.

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来源期刊

Current Opinion in Nephrology and Hypertension 医学-泌尿学与肾脏学

CiteScore

5.70

自引率

6.20%

发文量

132

审稿时长

6-12 weeks

期刊介绍： A reader-friendly resource, Current Opinion in Nephrology and Hypertension provides an up-to-date account of the most important advances in the field of nephrology and hypertension. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including pathophysiology of hypertension, circulation and hemodynamics, and clinical nephrology. Current Opinion in Nephrology and Hypertension is an indispensable journal for the busy clinician, researcher or student.