灵敏度体积是最大化电阻抗断层扫描数据重要性的关键因素

IF 2.3 4区 医学 Q3 BIOPHYSICS
Claire C Onsager, Chulin Wang, Charles Costakis, Can C Aygen, Lauren Lang, Suzan van der Lee, Matthew A Grayson
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引用次数: 0

摘要

目的。电阻抗层析成像(EIT)是一种无创成像方法,通过对异质导体外围的电测量值进行反演,绘制其内部电导率图。本文提出的 EIT 方法旨在通过引入灵敏度体积作为比较 EIT 测量方案的优劣势,从而提高计算速度和噪声容限。方法。每个测量值都对应模型空间中的一个灵敏度向量,因此测量值集合又对应模型空间中一个灵敏度体积的向量集合。最大灵敏度体积确定了具有最大灵敏度和最大相互正交性的测量协议。对可区分性标准进行了概括,以量化高灵敏度测量所增加的噪声容限。主要结果。灵敏度体积法可以最小化模型空间维度,使其与数据空间维度相匹配,并在由更多接触点定义的扩展测量空间内提高数据的重要性。意义重大。模型空间维度的缩小提高了计算效率,使层析反演的速度加快了几个数量级,而灵敏度的提高可容忍比标准方法大几个数量级的更高噪声水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sensitivity volume as figure-of-merit for maximizing data importance in electrical impedance tomography
Objective. Electrical impedance tomography (EIT) is a noninvasive imaging method whereby electrical measurements on the periphery of a heterogeneous conductor are inverted to map its internal conductivity. The EIT method proposed here aims to improve computational speed and noise tolerance by introducing sensitivity volume as a figure-of-merit for comparing EIT measurement protocols. Approach. Each measurement is shown to correspond to a sensitivity vector in model space, such that the set of measurements, in turn, corresponds to a set of vectors that subtend a sensitivity volume in model space. A maximal sensitivity volume identifies the measurement protocol with the greatest sensitivity and greatest mutual orthogonality. A distinguishability criterion is generalized to quantify the increased noise tolerance of high sensitivity measurements. Main result. The sensitivity volume method allows the model space dimension to be minimized to match that of the data space, and the data importance to be increased within an expanded space of measurements defined by an increased number of contacts. Significance. The reduction in model space dimension is shown to increase computational efficiency, accelerating tomographic inversion by several orders of magnitude, while the enhanced sensitivity tolerates higher noise levels up to several orders of magnitude larger than standard methods.
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来源期刊
Physiological measurement
Physiological measurement 生物-工程:生物医学
CiteScore
5.50
自引率
9.40%
发文量
124
审稿时长
3 months
期刊介绍: Physiological Measurement publishes papers about the quantitative assessment and visualization of physiological function in clinical research and practice, with an emphasis on the development of new methods of measurement and their validation. Papers are published on topics including: applied physiology in illness and health electrical bioimpedance, optical and acoustic measurement techniques advanced methods of time series and other data analysis biomedical and clinical engineering in-patient and ambulatory monitoring point-of-care technologies novel clinical measurements of cardiovascular, neurological, and musculoskeletal systems. measurements in molecular, cellular and organ physiology and electrophysiology physiological modeling and simulation novel biomedical sensors, instruments, devices and systems measurement standards and guidelines.
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