Zn[L-proline]2 作为水介质中通过环加成反应合成二氢吡喃噻唑衍生物的高效催化剂

IF 1.7 3区 化学 Q3 CHEMISTRY, ORGANIC
Hany M. Abd El-Lateef, Thomas Nady A. Eskander, Mohammad Saleh Hussein Alzubi, Mai M Khalaf, Mahmoud Abd El Aleem Ali Ali El-Remaily
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引用次数: 0

摘要

:本研究在绿色条件下,通过芳香醛与丙二腈和罗丹宁的单锅三组分反应,成功合成了一种与锌连接的氨基酸复合物,它是合成二氢吡喃噻唑衍生物的一种高效且可回收的催化剂。通过元素分析和光谱分析,阐明了新化合物的结构。该方法具有环境友好、成本低、操作简单、可重复使用和适用性广以及催化剂易于回收等特点。此外,还合成了一系列二氢吡喃噻唑衍生物。这种新方法具有安全、简单、稳定、条件温和、反应时间短、产率高和纯度高等显著优点,而且不使用任何有害溶剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Zn[L-proline]2 as an Efficient Catalyst for the Synthesis of Dihydro Pyrano Thiazole Derivatives via Cycloaddition Reaction in Aqueous Medium
: In the current study, a zinc-linked amino acid complex was successfully synthesized as an efficient and recoverable catalyst for the synthesis of dihydro pyrano thiazole derivatives via the reaction of an aromatic aldehyde with malononitrile and rhodanine in one-pot, three-component reaction under green conditions. The structures of the new compounds were elucidated by elemental and spectral analyses. Environmental friendliness, low cost, operational simplicity, extensive reusability and applicability, and easy recovery of the catalyst using simple methods are the critical features of this methodology. Moreover, a series of dihydro pyrano thiazole derivatives were synthesized. This new procedure has presented remarkable advantages in terms of safety, simplicity, stability, mild conditions, short reaction time, excellent yields, and high purity without using any hazardous solvents.
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来源期刊
Current Organic Chemistry
Current Organic Chemistry 化学-有机化学
CiteScore
3.70
自引率
7.70%
发文量
76
审稿时长
1 months
期刊介绍: Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.
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