The Effect of a Lipid Extract from the Marine Green Algae Codium fragile (Suringar) Hariot 1889 on Metabolic Reactions under Acute Stress

Abstract

The effect of a lipid extract isolated from the marine green algae Codium fragile (Suringar) Hariot on the liver and blood biochemical indicators in mice under the impact of acute stress (vertical fixation by the dorsal neck fold) was studied. The pharmacological effect of the C. fragile lipid extract was manifested in the restoration of lipid and carbohydrate metabolism, as well as in the normalization of the indicators of the endogenous antioxidant defense system under the effect of stress. The biological activity of the lipid extract of C. fragile is, probably, due to the action of its constituent polyunsaturated fatty acids of the ω-3 and ω-6 families. The lipid extract of C. fragile was not inferior to the reference Omega-3 preparation in restoring the body’s metabolic reactions caused by the impact of the stress; however, it showed higher antioxidant activity.