慢性肾脏病血管和瓣膜钙化的新治疗视角。

IF 2.2 3区医学 Q3 PERIPHERAL VASCULAR DISEASE

Current Opinion in Nephrology and Hypertension Pub Date : 2024-04-05 DOI:10.1097/mnh.0000000000000985

Sharon Huish, Smeeta Sinha

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引用次数: 0

摘要

血管和瓣膜钙化与慢性肾脏病（CKD）患者的心血管发病率和死亡率有关。目前还不确定减轻钙化的治疗策略。本综述概述了导致血管和瓣膜钙化的病理生理机制，探讨了治疗干预的作用机制，并报告了干预研究的最新成果。

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New therapeutic perspectives for vascular and valvular calcifications in chronic kidney disease.

Vascular and valvular calcification are associated with cardiovascular morbidity and mortality in people with chronic kidney disease (CKD). Uncertainty exists regarding therapeutic strategies to attenuate calcification. This review outlines the pathophysiological mechanisms contributing to vascular and valvular calcification, considers the mechanisms of action of therapeutic interventions, and reports the latest outcomes from interventional studies.

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来源期刊

Current Opinion in Nephrology and Hypertension 医学-泌尿学与肾脏学

CiteScore

5.70

自引率

6.20%

发文量

132

审稿时长

6-12 weeks

期刊介绍： A reader-friendly resource, Current Opinion in Nephrology and Hypertension provides an up-to-date account of the most important advances in the field of nephrology and hypertension. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including pathophysiology of hypertension, circulation and hemodynamics, and clinical nephrology. Current Opinion in Nephrology and Hypertension is an indispensable journal for the busy clinician, researcher or student.