{"title":"解码淋巴结：细胞病理学家在诊断可能的淋巴瘤中的关键作用","authors":"Udit K Naik, Y. Helen Zhang","doi":"10.1016/j.hpr.2024.300740","DOIUrl":null,"url":null,"abstract":"<div><p>Cytopathologists have assumed a progressively pivotal role in diagnosing lymphoproliferative disorders. This review outlines a concise approach to the work-up of suspected lymphoma in cytopathology practice, emphasizing the integration of cytomorphologic evaluation with ancillary studies. These include the application of rapid onsite evaluation (ROSE) for proper specimen triage, immunophenotyping through flow cytometry (FC) and immunohistochemistry (IHC), and molecular studies on cytology/small biopsy specimens. Furthermore, the review provides a brief introduction to the forthcoming WHO Reporting System in Lymph Node Cytopathology.</p></div>","PeriodicalId":100612,"journal":{"name":"Human Pathology Reports","volume":"36 ","pages":"Article 300740"},"PeriodicalIF":0.0000,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772736X24000124/pdfft?md5=d3138136158e6521228e736c6b5b94d7&pid=1-s2.0-S2772736X24000124-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Decoding lymph nodes: The crucial role of cytopathologists in diagnosing possible lymphoma\",\"authors\":\"Udit K Naik, Y. Helen Zhang\",\"doi\":\"10.1016/j.hpr.2024.300740\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Cytopathologists have assumed a progressively pivotal role in diagnosing lymphoproliferative disorders. This review outlines a concise approach to the work-up of suspected lymphoma in cytopathology practice, emphasizing the integration of cytomorphologic evaluation with ancillary studies. These include the application of rapid onsite evaluation (ROSE) for proper specimen triage, immunophenotyping through flow cytometry (FC) and immunohistochemistry (IHC), and molecular studies on cytology/small biopsy specimens. Furthermore, the review provides a brief introduction to the forthcoming WHO Reporting System in Lymph Node Cytopathology.</p></div>\",\"PeriodicalId\":100612,\"journal\":{\"name\":\"Human Pathology Reports\",\"volume\":\"36 \",\"pages\":\"Article 300740\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772736X24000124/pdfft?md5=d3138136158e6521228e736c6b5b94d7&pid=1-s2.0-S2772736X24000124-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Human Pathology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772736X24000124\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Pathology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772736X24000124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Decoding lymph nodes: The crucial role of cytopathologists in diagnosing possible lymphoma
Cytopathologists have assumed a progressively pivotal role in diagnosing lymphoproliferative disorders. This review outlines a concise approach to the work-up of suspected lymphoma in cytopathology practice, emphasizing the integration of cytomorphologic evaluation with ancillary studies. These include the application of rapid onsite evaluation (ROSE) for proper specimen triage, immunophenotyping through flow cytometry (FC) and immunohistochemistry (IHC), and molecular studies on cytology/small biopsy specimens. Furthermore, the review provides a brief introduction to the forthcoming WHO Reporting System in Lymph Node Cytopathology.
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