关注表达：蛋白酶激活受体-2通过PI3K/Akt/mTOR信号通路抑制自噬，从而促进肾小管上皮细胞炎症

IF 4.4 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochemical Journal Pub Date : 2024-04-10 DOI:10.1042/bcj20170272_eoc

Du, Chunyang, Zhang, Tao, Xiao, Xia, Shi, Yonghong, Duan, Huijun, Ren, Yunzhuo

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引用次数: 0

摘要

编辑部已经意识到这篇论文在科学性方面可能存在问题，因此在编辑部进行调查的同时，向读者发出了关注函。我们注意到，图 4C PAR2-OE 对照面板和图 4E Si-NC MHY1485 面板之间似乎有部分重复，图 7B Sham 和 UUO+rapa 面板之间也有重复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Expression of Concern: Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway

The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It has been noted that there seems to be a partial duplication between Figure 4C PAR2-OE control panel and Figure 4E Si-NC MHY1485 panel, as well as a duplication between Figure 7B Sham and UUO+rapa panels.

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来源期刊

Biochemical Journal 生物-生化与分子生物学

CiteScore

8.00

自引率

0.00%

发文量

255

审稿时长

1 months

期刊介绍： Exploring the molecular mechanisms that underpin key biological processes, the Biochemical Journal is a leading bioscience journal publishing high-impact scientific research papers and reviews on the latest advances and new mechanistic concepts in the fields of biochemistry, cellular biosciences and molecular biology. The Journal and its Editorial Board are committed to publishing work that provides a significant advance to current understanding or mechanistic insights; studies that go beyond observational work using in vitro and/or in vivo approaches are welcomed. Painless publishing: All papers undergo a rigorous peer review process; however, the Editorial Board is committed to ensuring that, if revisions are recommended, extra experiments not necessary to the paper will not be asked for. Areas covered in the journal include: Cell biology Chemical biology Energy processes Gene expression and regulation Mechanisms of disease Metabolism Molecular structure and function Plant biology Signalling