针对战斗和创伤性软组织损伤的多靶点无创光疗方法

Q3 Pharmacology, Toxicology and Pharmaceutics
Ashok Priyadarshi, Gaurav K. Keshri, Asheesh Gupta
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引用次数: 0

摘要

战斗创伤和软组织创伤因其严重性和复杂性带来了独特的挑战,因此需要探索快速、新颖的治疗干预措施。传统上,战斗创伤都是通过侵入性外科手术来处理的,这可能会带来并发症,并延长恢复时间。然而,非侵入性治疗方式的进步为更有效、高效地处理战斗创伤提供了新的可能性。本文旨在全面概述治疗战斗创伤和外部创伤的无创、无药、生物物理治疗方法,重点介绍这些方法的益处、疗效和潜在应用。光生物调制疗法(PBMT)的非侵入性和良好的安全性使其成为治疗战斗创伤的一个有吸引力的选择。有证据表明,光生物调控疗法在促进组织修复、减少疼痛、炎症、氧化应激和促进功能恢复方面具有显著疗效。总之,本综述强调了使用双波长/多波长光能的无创生化肉毒杆菌疗法作为治疗创伤性软组织和战斗损伤的重要方法的巨大潜力,并广泛探讨了相关的机理认识。进一步研究将潜在药理制剂与 PBMT 结合使用的组合疗法、最佳辐照方案和其他基于能量的治疗模式,将有助于将潜在的非侵入性治疗干预措施转化为临床应用,以治疗战斗和创伤性损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multi Targeted Non Invasive Photoceutical Therapeutic Approach for Combat and Traumatic Soft Tissue Injuries
Combat and soft tissue traumatic injuries pose unique challenges in terms of their severity, complexity, and thus need for the exploration of rapid, novel therapeutic interventions. Traditionally, combat injuries have been managed through invasive surgical procedures associated with potential complications and prolonged recovery times. However, advancements in non-invasive treatment modalities have opened up new possibilities for managing combat injuries more effectively and efficiently. The present article aims to provide a comprehensive overview of non-invasive, drug-free, biophysical therapeutic approaches for combat and external traumatic injuries, focusing on their benefits, efficacy, and potential applications. The non-invasive nature and favourable safety profile of photobiomodulation therapy (PBMT) make it an attractive option for combat injury management. The evidence on underlying mechanistic insights supports the efficacy of PBMT in promoting tissue repair, reducing pain, inflammation, oxidative stress, and facilitating functional recovery. In conclusion, the present review highlights the significant potential of non-invasive PBMT using dual/multi-wavelength light energy as a valuable therapeutic approach for traumatic soft tissue and combat injuries and extensively explores associated mechanistic insights. Further research on combination therapies using potential pharmacological agents in conjunction with PBMT, with optimal irradiation protocols and other energy-based healing modalities will favour the translation of potential non-invasive healing intervention for combat and traumatic injuries in clinical applications.
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来源期刊
Defence Life Science Journal
Defence Life Science Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.80
自引率
0.00%
发文量
26
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