恶性黑色素瘤自动诊断的计算智能方法

Samy Bakheet, Mahmoud A. Mofaddel, A. El-Nagar
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引用次数: 0

摘要

:皮肤癌是人类最常见、最危险的癌症。在各种皮肤恶性肿瘤中,黑色素瘤的恶性程度尤为严重,是造成大量癌症相关死亡的原因。皮肤癌的早期发现对降低死亡率和挽救生命起着至关重要的作用。因此,由机器学习算法驱动的计算机辅助诊断(CAD)系统有助于及早发现黑色素瘤。在本文中,我们提出了一种通过开发全自动计算机辅助诊断系统来识别黑色素瘤的创新方法。为了提高输入皮肤镜图像的整体质量,我们采用了一系列预处理技术,如中值滤波和底帽滤波。此外,我们还采用了一种基于著名的大津阈值技术的自适应分割方法,以从改进后的输入图像中准确提取疑似皮损区域。然后,我们使用局部二进制模式(LBP)特征提取方法来描述分割后的皮损特征。这项技术能让我们有效地捕捉到皮损的相关信息。最后,将提取的特征插入决策树(DT)分类器,将给定皮肤镜图像中的每个黑色素细胞皮肤病变分为良性或黑色素瘤。采用 10 倍交叉验证方法对提出的方法进行了有效测试和验证,平均诊断准确率、灵敏度和特异性分别达到 90.35%、88.47% 和 86.28%。实验利用 MATLAB 环境在 ISIC 数据库中进行,该数据库包含可疑的黑色素瘤皮肤癌病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Computational Intelligence Approach for Automatic Malignant Melanoma Diagnostics
: Skin cancer is the most prevalent and perilous kind of cancer in human beings. Among the various types of dermatological malignancy, melanomas are particularly malignant and responsible for a significant number of cancer-related deaths. Early skin cancer detection plays a crucial role in reducing mortality rates and saving lives. So, Computer-Aided Diagnosis (CAD) systems that are driven by machine learning algorithms can help to detect melanoma early. In this article, we propose an innovative approach to melanoma recognition through the development of a fully automatic CAD system. To elevate the overall quality of input dermatoscopic images, we apply a series of preprocessing techniques such as median filtering and bottom-hat filtering. Besides that, an adaptive segmentation method based on the well-known Otsu thresholding technique is conducted to accurately extract suspected skin lesion regions from the improved input image. Then, we use the Local Binary Pattern (LBP) feature extraction method to characterize segmented skin lesions. This technique enables us to capture relevant information from the lesions effectively. Ultimately, the extracted features are inserted into a Decision Tree (DT) classifier to categorize each melanocytic cutaneous lesion in a given dermatoscopic image as either benign or melanoma. The proposed method is effectively tested and verified using a 10-fold cross-validation approach, achieving 90.35%, 88.47%, and 86.28% for average diagnostic accuracy, sensitivity, and specificity, respectively. The experimentation is conducted on the ISIC database, which contains suspect melanoma skin cancer cases, utilizing the MATLAB environment.
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