坏死性筋膜炎患者 LRINEC 评分的有效性及其与预后的相关性

IF 0.6 Q4 SURGERY
Sumit Kumar, Suhas Agarwal, Gaurav Patel, Ishan Sehgal, Sandeep Gara, Pushkar Yadav
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引用次数: 0

摘要

摘要背景:坏死性筋膜炎是一种迅速升级的筋膜炎症感染,继发皮下组织坏死。为了帮助诊断,我们设计了坏死性筋膜炎实验室风险指标(LRINEC)评分系统,对患者发病时感染的可能性进行分层。研究目的研究旨在调查和量化 LRINEC 评分系统与坏死性筋膜炎患者截肢需求、住院时间和死亡率等结果之间的关系。研究方法共收治了 90 名初步诊断为坏死性筋膜炎的患者。根据患者发病时的六个实验室变量计算每个病例的 LRINEC 评分。根据 LRINEC 评分将入选患者分为三组。比较三组患者在死亡率、住院时间、清创次数和截肢需求方面的差异。结果如下年龄增大、男性、糖尿病对坏死性筋膜炎患者的预后影响较差。截肢率和死亡率与 LRINEC 评分越高越相关。结论LRINEC 评分有助于根据严重程度有条理地将患者分为低危、中危和高危等风险类别,并及时采取适当的治疗措施,如手术清创。LRINEC 评分是一个强大的指数,能够检测出坏死性筋膜炎的早期病例,而且简单易用,适合常规使用。它是一种简化的床旁诊断工具,可用于坏死性筋膜炎患者的早期诊断和预后预测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of LRINEC Scoring in Patients of Necrotizing Fasciitis and its Correlation with the Outcome
ABSTRACTBackground: Necrotizing fasciitis is an expeditiously escalating inflammatory infection of the fascia, with secondary necrosis of the subcutaneous tissues. To aid diagnosis, the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scoring system was devised to stratify the likelihood of infection in patients on presentation. Objectives: Study aimed to investigate and quantify the relationships between the LRINEC scoring system and the outcomes such as need for amputation, length of hospital and mortality stay in patients with necrotizing fasciitis. Method: A total number of 90 Patients were admitted with a provisional diagnosis of necrotizing fasciitis. LRINEC score was calculated for each case based on six laboratory variables at the time of presentation. Enrolled patients were divided into three groups on the basis of LRINEC score. The differences in mortality, length of hospitalization, number of debridement and the need of amputation between these groups were compared. Results: Increasing age, male gender, DM has a poor prognosis in the outcome of necrotizing fasciitis patients. The amputation rates and mortality rates are better correlated with higher LRINEC score. Conclusion: The LRINEC score helps in stratifying the patients into risk categories such as low risk, moderate risk and high risk categories, according to severity in a much organized way and the appropriate management like surgical debridement can be started timely. LRINEC score is a robust index that is capable of detecting early cases of necrotizing fasciitis and is simple enough for routine use. It is a simplified bedside diagnostic tool for early diagnosis and prediction of outcome in patients of necrotizing fasciitis.
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CiteScore
1.10
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