化疗引起的周围神经病变对多发性骨髓瘤患者生活质量的影响

Global journal for research analysis Pub Date : 2024-01-15 DOI:10.36106/gjra/3505631

Abhishekh Pratap Singh, Anoop Mantri, Pooja Gandhi

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引用次数: 0

摘要

研究目的本研究旨在评估多发性骨髓瘤（MM）患者化疗诱发周围神经病变（CIPN）的症状及其对健康相关生活质量（HRQOL）的影响：方法：利用欧洲癌症研究和治疗组织的CIPN生活质量问卷（QLQ-CIPN20）和欧洲癌症研究和治疗组织的多发性骨髓瘤模块（QLQ-MY20），对一家三级医院的MM患者进行了横断面调查。数据采用描述性统计。结果：26 名患者参与了研究，其中 61.5% 为男性。平均年龄为 64.34 ± 8.49 岁。CIPN症状包括刺痛、麻木和行走困难。人力资源质量和生活质量方面的挑战包括骨痛、背痛、感觉不适、脱发以及对健康和死亡率的担忧。结论：MM 患者会出现 CIPN 症状，影响他们的 HRQOL。在常规临床实践中，将 CIPN 评估作为患者报告的结果至关重要。

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THE INFLUENCE OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY ON QUALITY OF LIFE IN INDIVIDUALS WITH MULTIPLE MYELOMA

Objective: This study aimed to evaluate the symptoms of chemotherapy-induced peripheral neuropathy (CIPN) and its impact on health-related quality of life (HRQOL) in multiple myeloma (MM) patients. Methods: A cross-sectional survey was conducted among MM patients at a tertiary care hospital, utilizing the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire for CIPN scale (QLQ-CIPN20) and the EORTC multiple myeloma module (QLQ-MY20). Descriptive statistics were used for data presentation. Results: 26 patients participated, with 61.5% being male. The average age was 64.34 ± 8.49 years. CIPN symptoms included tingling, numbness, and difculty in walking. HRQOL challenges encompassed bone pain, back pain, feeling ill, hair loss, and concerns about health and mortality. Conclusion: MM patients experience CIPN symptoms, impacting their HRQOL. Incorporating CIPN assessments as patient-reported outcomes is crucial in routine clinical practice.

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Global journal for research analysis

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