泵上冠状动脉旁路移植术与非泵上冠状动脉旁路移植术围手术期血清乳酸水平的比较

Hymavathi Varla, Rahul Nethikar, Vijaya Mohan Canjeevaram
{"title":"泵上冠状动脉旁路移植术与非泵上冠状动脉旁路移植术围手术期血清乳酸水平的比较","authors":"Hymavathi Varla, Rahul Nethikar, Vijaya Mohan Canjeevaram","doi":"10.36106/gjra/8400336","DOIUrl":null,"url":null,"abstract":"Coronary artery bypass grafting (CABG) can be performed with the use of cardiopulmonary bypass (onpump CABG) or without (off-pump CABG). Lactate is used as a marker for oxygen deciency in anaerobic\nmetabolism at the tissue level. Increase in tissue lactate concentration is associated with cellular dysfunction due to the\ndepletion of high energy phosphate compounds. This Institution based Retrospective study was done to Compare the peri -\noperative serum lactate levels in patients undergoing On-pump versus Off-pump CABG Surgery. Total 20 patients were\nanalysed with mean age of 56.35 +- 4.33 years. EURO score-2 shows 0.85 +- 0.28 and 1.21 +- 0.54 in On-pump and Off-pump\nrespectively. EURO score-2 is high in Off-pump when compared with On-pump and this ndings are statistically not signicant\n(p: 0.07). Peak lactate levels in On-pump& Off-pump CABG are 4.7& 5.8 mmol/dl respectively. Older studies showed that there\nwas a signicant association seen between lactate level and CPB. Off-pump surgery may improve short-term outcomes such as\nrenal failure and stroke. In our study, there were no signicant differences in postoperative patterns of release of Lactates in\npatients with On-pump v/s Off-pump","PeriodicalId":12664,"journal":{"name":"Global journal for research analysis","volume":"4 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"COMPARISION OF PERIOPERATIVE SERUM LACTATE LEVEL IN ON-PUMP VERSUS OFF-PUMP CORONARY ARTERY BYPASS GRAFT\",\"authors\":\"Hymavathi Varla, Rahul Nethikar, Vijaya Mohan Canjeevaram\",\"doi\":\"10.36106/gjra/8400336\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Coronary artery bypass grafting (CABG) can be performed with the use of cardiopulmonary bypass (onpump CABG) or without (off-pump CABG). Lactate is used as a marker for oxygen deciency in anaerobic\\nmetabolism at the tissue level. Increase in tissue lactate concentration is associated with cellular dysfunction due to the\\ndepletion of high energy phosphate compounds. This Institution based Retrospective study was done to Compare the peri -\\noperative serum lactate levels in patients undergoing On-pump versus Off-pump CABG Surgery. Total 20 patients were\\nanalysed with mean age of 56.35 +- 4.33 years. EURO score-2 shows 0.85 +- 0.28 and 1.21 +- 0.54 in On-pump and Off-pump\\nrespectively. EURO score-2 is high in Off-pump when compared with On-pump and this ndings are statistically not signicant\\n(p: 0.07). Peak lactate levels in On-pump& Off-pump CABG are 4.7& 5.8 mmol/dl respectively. Older studies showed that there\\nwas a signicant association seen between lactate level and CPB. Off-pump surgery may improve short-term outcomes such as\\nrenal failure and stroke. In our study, there were no signicant differences in postoperative patterns of release of Lactates in\\npatients with On-pump v/s Off-pump\",\"PeriodicalId\":12664,\"journal\":{\"name\":\"Global journal for research analysis\",\"volume\":\"4 3\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Global journal for research analysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36106/gjra/8400336\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global journal for research analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36106/gjra/8400336","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

冠状动脉旁路移植术(CABG)可以使用心肺旁路(泵上CABG),也可以不使用心肺旁路(泵下CABG)。乳酸是组织水平无氧代谢中氧去ciency 的标志物。组织乳酸浓度的增加与高能磷酸化合物耗竭导致的细胞功能障碍有关。这项基于医院的回顾性研究旨在比较接受体外循环和非体外循环 CABG 手术患者的围手术期血清乳酸水平。共对 20 名患者进行了分析,他们的平均年龄为 56.35 +- 4.33 岁。EURO评分-2在体外循环和非体外循环中分别为0.85 +- 0.28和1.21 +- 0.54。EURO评分-2在Off-pump比On-pump高,但这,在统计学上无显著cant(p: 0.07)。On-pump 和 Off-pump CABG 的乳酸峰值分别为 4.7 和 5.8 mmol/dl。较早的研究表明,乳酸水平与 CPB 有显著。非泵手术可改善肾功能衰竭和中风等短期预后。在我们的研究中,使用开泵手术和使用非开泵手术的患者术后乳酸盐释放模式没有显cant 的差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COMPARISION OF PERIOPERATIVE SERUM LACTATE LEVEL IN ON-PUMP VERSUS OFF-PUMP CORONARY ARTERY BYPASS GRAFT
Coronary artery bypass grafting (CABG) can be performed with the use of cardiopulmonary bypass (onpump CABG) or without (off-pump CABG). Lactate is used as a marker for oxygen deciency in anaerobic metabolism at the tissue level. Increase in tissue lactate concentration is associated with cellular dysfunction due to the depletion of high energy phosphate compounds. This Institution based Retrospective study was done to Compare the peri - operative serum lactate levels in patients undergoing On-pump versus Off-pump CABG Surgery. Total 20 patients were analysed with mean age of 56.35 +- 4.33 years. EURO score-2 shows 0.85 +- 0.28 and 1.21 +- 0.54 in On-pump and Off-pump respectively. EURO score-2 is high in Off-pump when compared with On-pump and this ndings are statistically not signicant (p: 0.07). Peak lactate levels in On-pump& Off-pump CABG are 4.7& 5.8 mmol/dl respectively. Older studies showed that there was a signicant association seen between lactate level and CPB. Off-pump surgery may improve short-term outcomes such as renal failure and stroke. In our study, there were no signicant differences in postoperative patterns of release of Lactates in patients with On-pump v/s Off-pump
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信